July/August 2022- Volume 18, Issue 7

In this Issue

Editor's Focus

A honeybee sits on a honeycomb.

From Honeybees to Humans: Imaging gene expression in the brain

From Honeybees to Humans: Imaging gene expression in the brain

Entomologists and computer engineers developed a novel imaging method for analyzing gene expression in live brains.
Three menstrual pads are shown against a pink background with three hands clasping the pads. A pink callout is shown coming from the pad on the left. Three drops of blood are shown on the center pad, and the pad on the right has a large red circle on it.

Menstrual blood holds the key to better diagnostics

Menstrual blood holds the key to better diagnostics

Usually thrown away as waste, menstrual blood may help clinicians non-invasively monitor and diagnose a multitude of health conditions from diabetes and endometriosis to cancer.

Editors Insight

A scientist uses a magnifying glass to observe a man at a desk.

Genetic discrimination and Snapchat

Genetic discrimination and Snapchat

What do 23andMe and Snapchat have in common? They both collect very personal information about their users. Do the benefits outweigh the risks?

Biologics

A man wearing a mask inside a doctor’s office smells a lemon.

Sniffing plasma helps COVID-19 patients smell again

Sniffing plasma helps COVID-19 patients smell again

People with COVID-19 sometimes lose their sense of smell. But a clinical researcher has a possible solution: the patient’s own blood.
A model of the spikey-looking structure of nanosyringes released by the P. luteoviolacea species of bacteria.

Bacterial nanosyringes are drug and delivery all in one

Bacterial nanosyringes are drug and delivery all in one

Nanosyringes produced by some bacterial species naturally inject proteins into eukaryotic cells, paving a new frontier for biologic drug delivery.

Biomarkers

Hundreds of antibodies swarm a virus as a part of the body’s immune response to infection.

Predicting immune responses to vaccination

Predicting immune responses to vaccination

Armed with a machine learning and systems biology approach, John Tsang studies how past infections and vaccinations shape an individual’s immune response to future vaccines.

Epigenetics

A DNA helix in white is drawn over a blue background. The individual DNA bases are shown.

A blueprint for a new epigenomic era

A blueprint for a new epigenomic era

A recent effort to sequence the entire human genome also revealed how it can be modified.
Computerized, multi-coloured image of DNA and its epigenetic modifications.

Milestone: Pulling down answers to biological mysteries with ChIP

Milestone: Pulling down answers to biological mysteries with ChIP

Through many innovations over the past 40 years, ChIP rapidly evolved to become a powerful tool for understanding the epigenome.

Phenotype Screens

A group of pink flamingos stand together in a lake.

Metabolomics open a window into better cancer treatments

Metabolomics open a window into better cancer treatments

Chemical biologist Stefano Tiziani uses metabolomics to identify new combination cancer treatments and to predict which patients will respond best to chemotherapy.
An abstract illustration showing the brain creating new ideas and solutions

Patient cells and serum create better Alzheimer’s disease models

Patient cells and serum create better Alzheimer’s disease models

Many potential treatments for Alzheimer’s disease have been found using mouse models, but they often don’t translate well to humans. Will organoids provide the answers that neuroscientists need to develop new treatments?
Scientists and clinicians examine an individual’s heart with various tools including stethoscopes and EKG machines.

A nanoengineered heart chamber 

A nanoengineered heart chamber 

A new heart-on-a-chip gives scientists an up-close look at the beating human heart from the comfort of their lab benches.
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