July/August 2022 Volume 18, Issue 7

July/August 2022 : Volume 18 : Issue 7

Volume 18, Issue 7 | July/August 2022

July/August 2022

In this Issue

Biologics

A model of the spikey-looking structure of nanosyringes released by the P. luteoviolacea species of bacteria.

Bacterial nanosyringes are drug and delivery all in one

Nanosyringes produced by some bacterial species naturally inject proteins into eukaryotic cells, paving a new frontier for biologic drug delivery.
A man wearing a mask inside a doctor’s office smells a lemon.

Sniffing plasma helps COVID-19 patients smell again

People with COVID-19 sometimes lose their sense of smell. But a clinical researcher has a possible solution: the patient’s own blood.

Editor's Focus

Three menstrual pads are shown against a pink background with three hands clasping the pads. A pink callout is shown coming from the pad on the left. Three drops of blood are shown on the center pad, and the pad on the right has a large red circle on it.

Menstrual blood holds the key to better diagnostics

Usually thrown away as waste, menstrual blood may help clinicians non-invasively monitor and diagnose a multitude of health conditions from diabetes and endometriosis to cancer.
A honeybee sits on a honeycomb.

From Honeybees to Humans: Imaging gene expression in the brain

Entomologists and computer engineers developed a novel imaging method for analyzing gene expression in live brains.

Epigenetics

A DNA helix in white is drawn over a blue background. The individual DNA bases are shown.

A blueprint for a new epigenomic era

A recent effort to sequence the entire human genome also revealed how it can be modified.
Computerized, multi-coloured image of DNA and its epigenetic modifications.

Milestone: Pulling down answers to biological mysteries with ChIP

Through many innovations over the past 40 years, ChIP rapidly evolved to become a powerful tool for understanding the epigenome.

Biomarkers

Hundreds of antibodies swarm a virus as a part of the body’s immune response to infection.

Predicting immune responses to vaccination

Armed with a machine learning and systems biology approach, John Tsang studies how past infections and vaccinations shape an individual’s immune response to future vaccines.

Phenotype Screens

Scientists and clinicians examine an individual’s heart with various tools including stethoscopes and EKG machines.

A nanoengineered heart chamber 

A new heart-on-a-chip gives scientists an up-close look at the beating human heart from the comfort of their lab benches.
An abstract illustration showing the brain creating new ideas and solutions

Patient cells and serum create better Alzheimer’s disease models

Many potential treatments for Alzheimer’s disease have been found using mouse models, but they often don’t translate well to humans. Will organoids provide the answers that neuroscientists need to develop new treatments?
A group of pink flamingos stand together in a lake.

Metabolomics open a window into better cancer treatments

Chemical biologist Stefano Tiziani uses metabolomics to identify new combination cancer treatments and to predict which patients will respond best to chemotherapy.

Editors Insight

A scientist uses a magnifying glass to observe a man at a desk.

Genetic discrimination and Snapchat

What do 23andMe and Snapchat have in common? They both collect very personal information about their users. Do the benefits outweigh the risks?
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Clear sample tubes are shown in a clear tote with red lids in a sample prep robot with a blue and silver industrial lab background.

The crucial role of sample preparation in biotherapy manufacturing

Discover how better sample preparation can unlock improved assay accuracy and analytical results.
A black mosquito is shown on pink human skin against a blurred green backdrop.

Discovering deeper insights into malaria research

Malaria continues to drive urgent research worldwide, with new therapies and tools emerging to combat the parasite’s complex lifecycle and global burden.
Three burgundy round and linear conformations of oligonucleotides are shown against a black background.

Accelerating RNA therapeutic testing with liver microphysiological platforms

Researchers can now study oligonucleotide delivery and efficacy in a system that models a real human liver.
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