July 2024 Volume 20, Issue 4
Volume 20, Issue 4 | July 2024
July 2024
In this Issue
Editor's Focus
Profiling the spatial secrets of the placenta
While vital for a healthy pregnancy, the placenta is not well understood. Researchers now take advantage of spatial biology approaches to plumb its secrets.
Milestone: The origins of oncolytic viral therapy
Since their discovery in the 1890s, viruses have intrigued scientists as potential cancer-killing agents.Editors Insight
Science stands on shaky shoulders with research misconduct
Research misconduct poisons the well of scientific literature, but finding systemic ways to change the current “publish or perish” culture will help.Clinical Trials
A new frontier in monoclonal antibody delivery
New research aims to make antibody drug delivery as precise and efficient as the antibodies themselves.
After 70 years, a new class of drugs for schizophrenia
A new type of drug for schizophrenia could finally be approved in September. Others may not be far behind.Biologics
Probiotics to alleviate depression
Researchers target the gut to see if they can treat depression with fewer side effects and less stigma than current drugs.
CAR T cells in a SNAP
A modular CAR T cell could make cancer therapy safer and more effective.
Decoding the molecular complexity of biologics
Biologics like monoclonal antibodies and mRNA vaccines are complex drugs. Yongchao Su uses biophysical tools and innovative strategies to understand them better.Ophthamology
Mini-retinas model human disease in a dish
Researchers use retinal organoids to screen drugs and hope to transplant them into the eyes of people with blindness in the coming years.
Restoring color vision with gene therapy
People with achromatopsia have never seen color. Restorative gene therapies have had mixed success, leaving researchers wondering why.
The optic nerve may help protect the brain from sickness
Researchers discovered an immunological connection between the eye and the brain that could lead to new therapeutics for central nervous system diseases.Spatial Biology
Bioprinting tumors to fight them
3D bioprinted models of the tumor microenvironment could make the preclinical research process more reliable and accelerate translation to the clinic.
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The crucial role of sample preparation in biotherapy manufacturing
Discover how better sample preparation can unlock improved assay accuracy and analytical results.
Discovering deeper insights into malaria research
Malaria continues to drive urgent research worldwide, with new therapies and tools emerging to combat the parasite’s complex lifecycle and global burden.
Accelerating RNA therapeutic testing with liver microphysiological platforms
Researchers can now study oligonucleotide delivery and efficacy in a system that models a real human liver.
