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July 2024 Volume 20, Issue 4

Volume 20, Issue 4 | July 2024

July 2024

In this Issue

Editor's Focus

An ultra-fast photoacoustic microscopy image of a mouse placenta taken via a window in the mouse’s abdomen.

Profiling the spatial secrets of the placenta

While vital for a healthy pregnancy, the placenta is not well understood. Researchers now take advantage of spatial biology approaches to plumb its secrets.

Alice Moore, a researcher at Memorial Sloan Kettering Cancer Center, first demonstrated that viruses could kill tumor cells in living animals.

Milestone: The origins of oncolytic viral therapy

Since their discovery in the 1890s, viruses have intrigued scientists as potential cancer-killing agents.

Editors Insight

Science stands on shaky shoulders with research misconduct

Research misconduct poisons the well of scientific literature, but finding systemic ways to change the current “publish or perish” culture will help.

Clinical Trials

Antibodies made up of blue, green, and orange strings sit against a blue background.

A new frontier in monoclonal antibody delivery

New research aims to make antibody drug delivery as precise and efficient as the antibodies themselves.

Overlapping profiles of yellow and blue faces are on top of a multicolored striped background.

After 70 years, a new class of drugs for schizophrenia

A new type of drug for schizophrenia could finally be approved in September. Others may not be far behind.

Biologics

A drawing of a girl holding her head in her arms while sitting on the floor.

Probiotics to alleviate depression

Researchers target the gut to see if they can treat depression with fewer side effects and less stigma than current drugs.

Avani Parikh wears a lab coat while conducting an experiment at a lab bench.

CAR T cells in a SNAP

A modular CAR T cell could make cancer therapy safer and more effective.

Decoding the molecular complexity of biologics

Biologics like monoclonal antibodies and mRNA vaccines are complex drugs. Yongchao Su uses biophysical tools and innovative strategies to understand them better.