July 2012- Volume 8, Issue 7

July 2012

In this Issue

Diagnostics

Exosome chooses Life

Exosome chooses Life

Exosome Diagnostics will use Life Technologies’ real-time PCR platform for exosome biofluid oncology diagnostics

Last man standing

Last man standing

LabCorp acquires MEDTOX Scientific, one of two remaining major independent clinical labs

Spanning the melanoma continuum

Spanning the melanoma continuum

HTG Molecular Diagnostics, John Wayne Cancer Institute partner to commercialize melanoma signatures

In their blood

In their blood

Biocartis, Philips and Wellcome Trust to develop automated blood-based assay system for monitoring tumor load

Casting a clinical eye

Casting a clinical eye

Agilent to acquire Dako for $2.2 billion as it looks to growth in clinical diagnostics market

Global News

Art of the deals

Art of the deals

Takeda announces plans to acquire Brazil’s Multilab just before closing deal on U.S.-based URL Pharma

Brazil beckons to Belgium

Brazil beckons to Belgium

Belgium-based UCB partners with emerging market Brazil-based Meizler to create Meizler UCB Biopharma

Just what the doctor ordered

Just what the doctor ordered

Dr. Reddy’s, Merck to collaborate on biosimilars

Probing the bowels of disease

Probing the bowels of disease

Crohn’s and Colitis Foundation of Canada, Vertex Pharmaceuticals lead industry-academic quest to uncover biology of IBD

Tools & Technology

No more ‘garbage in, garbage out’

No more ‘garbage in, garbage out’

Seeking better data analysis in histology, Flagship Biosciences acquires IHCtech

Pop-up informatics

Pop-up informatics

Robust SaaS workspace accelerates and streamlines collaborative drug discovery for virtual teams

A*STAR for Hitachi

A*STAR for Hitachi

Hitachi and Singapore’s A*STAR design novel method to reduce genome data storage

Harnessing ISH and IHC

Harnessing ISH and IHC

Affymetrix and Leica collaborate on RNA in-situ hybridization tissue assay for research use

Corning announces cell-culture automation collaboration with TAP Biosystems

Corning announces cell-culture automation collaboration with TAP Biosystems

Corning Life Sciences announced last month that it has entered into a collaboration with TAP Biosystems to provide a manufacturing automation solution for large-scale, attachment-dependent cell culture

Research & Development

A pair of Northern lights

A pair of Northern lights

Canada’s Actium Research, McMaster University announce partnership

Racking the brain

Racking the brain

Researchers at MD Anderson Cancer Center, two California biotechs lead effort to create new treatments for glioblastoma multiforme

Taking a long, hard look at HER

Taking a long, hard look at HER

GE Healthcare and Affibody team up on HER2-specific PET imaging agent for breast and gastric cancer

On the hunt for Huntington’s disease therapy

On the hunt for Huntington’s disease therapy

Lundbeck, CHDI to conduct preclinical studies on a Lundbeck investigative compound

Tau Therapeutics and NCI launch Phase Ib trial in brain cancer

Tau Therapeutics and NCI launch Phase Ib trial in brain cancer

Tau Therapeutics LLC, a pharmaceutical company developing T-type calcium channel inhibitors for the treatment of solid tumors, announced today that it has opened enrollment for a Phase Ib clinical trial

International team tackles cancer

International team tackles cancer

BMS launches global academic collaboration to focus on immuno-oncology

Omics & Systems Biology

Does persistence pay off?

Does persistence pay off?

GSK extends offer to acquire Human Genome Sciences, details remain the same

New on the singles scene

New on the singles scene

Broad Institute and Fluidigm launch new research center to focus on mammalian single-cell genomics

Real-time liquid biopsy

Real-time liquid biopsy

Fluxion Biosciences and Rubicon Genomics to collaborate on tracking down circulating tumor cells

An A+ partnership on hemophilia B

An A+ partnership on hemophilia B

Baxter, Chatham partner on Factor IX gene therapy

From pilot to partners

From pilot to partners

Novartis, Foundation Medicine build on oncology genome analysis collaboration

Government Watch

Taking the fifth

Taking the fifth

PDUFA legislation is reauthorized by House and Senate for fifth time since 1992

I spy with my little eye …

I spy with my little eye …

FDA’s I-Spy 2 trial aims to make cancer drug approvals faster, more efficient

California bill seeks restrictions on genetic data

California bill seeks restrictions on genetic data

Some researchers concerned that broad provisions will impede genetic research

Commentary

Meeting the need for large-scale production of stem cells

Meeting the need for large-scale production of stem cells

As demand for stem cells for both drug discovery and clinical applications grows, effectively translating the promise of stem cells into therapeutic reality will require large-scale “industrialized” production under tightly controlled conditions.

Out of Order: Good news and good luck

Out of Order: Good news and good luck

Bad news isn’t inherently bad just because it’s not what we expected or wanted, and it should be allowed to inform our subsequent decisions just as much as the good news. We’re just going to have to learn to discuss it like adults.

Editor's Focus

Crohn’s a very personal disease

Crohn’s a very personal disease

My sister Nina has Crohn’s disease, and a severe form of it at that. She never complained much -- she even had a sense of humor about a disease that some people consider unfit for polite conversation.

Special Reports

Epigenetics: Half of the picture (PART 2)

Epigenetics: Half of the picture (PART 2)

Science plugs stem cells into epigenetic opportunities that control various disease states

Epigenetics: Half of the picture (PART 1)

Epigenetics: Half of the picture (PART 1)

Science plugs stem cells into epigenetic opportunities that control various disease states
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