July 2009 Volume 5, Issue 7

Volume 5, Issue 7 | July 2009

July 2009

In this Issue

Global News

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Novartis nabs Ebewe

Swiss drugmaker expands specialty generics business with $1.2 billion purchase of injectable drug unit
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Deuterium discovery deal

GSK and Concert Pharmaceuticals to develop deuterium-modified drugs in deal worth up to $1 billion
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France’s Cerep inks deal with Lilly

Platform includes screening capabilities for 250 targets with assays for a wide range of diseases
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Sciele claims Victory in pain battle with $150 million acquisition

Atlanta-based Sciele Pharma acquires Victory, aligns with Shionogi’s pain management focus
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Boehringer Ingelheim and DxS in lung cancer diagnostic deal

Companies partner on companion diagnostic to identify EGFR mutations in patients with lung cancer
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Xenon inks $184 million cardiovascular disease collaboration with Merck

On June 11, Xenon announced a strategic alliance with Merck & Co. Inc., through an affiliate, to discover and develop novel small-molecule candidates for the potential treatment of cardiovascular disease.

Genomics & Proteomics

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The one percent solution

Roche's 454 Life Sciences and SeqWright bring their technologies to bear on the human exome to help understand dilated cardiomyopathy
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Mission: Gaps no more

Broad Institute researchers employ Roche-454 technology to close some gaps in the human genome that resist traditional bacterial cloning methods
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Advancing Avestagenome

Avesthagen and Harvard agree to share genomics knowledge, services
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A story of cancer, canines and collaboration

North Carolina State University and UNC Lineberger team up to combat cancer in man—and man’s best friend
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Your own personal genome

Illumina launches $48K consumer sequencing
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The 'democratization' of genetic research

23andMe, PatientsLikeMe team up to study Parkinson's disease, pursue personal genetics

Research & Development

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Taking their gloves off

AstraZeneca, Merck form collaboration to investigate novel combination anticancer regimen
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Targeted immunotherapy tag team

Genentech and Bayhill Therapeutics partner on development of antigen-specific immunotherapy candidate for type 1 diabetes in deal that could exceed $350 million
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Heavy water keys collaboration between Bristol-Myers Squibb and KineMed

Companies to use stable isotope technology to identify biomarkers that can be used to treat Alzheimer\'s
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Celldex Therapeutics acquires CuraGen and its oncology antibodies for $94.5 million

Deal also bolsters Celldex's financials, allowing it to advance clinical programs into 2012
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Taking aim at tuberculosis

TB Alliance announces four drug discovery collaborations to stock TB pipeline
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Breast cancer Dx beyond borders

ExonHit purchases exclusive rights from Institut Gustave Roussy for novel breast cancer diagnostic assay

Informatics

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A new extension for Microsoft

Software giant to acquire assets of Rosetta Biosoftware from Merck, boosting Amalga Life Sciences platform
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Quite the pair

Ingenuity-Integromics integration offers comprehensive genomics analysis
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Down the in silico discovery pathway

Gene Network Sciences, UCSF use Bayesian network model for project
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For E-Notebook system, it's official

University of Antwerp selects CambridgeSoft's E-Notebook for university-wide research use
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Creating a cheminformatics connection

University of Cambridge selects IDBS as its data management provider and commences an R&D collaboration
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Data deluge dam

GenoLogics and SAS team up to create end-to-end analysis solution for large genomic data sets

Commentary

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Fixing the U.S. Food and Drug Administration: More money and power—or more competition?

Objectively measured, the FDA is overfunded and overstaffed. The FDA employs too many people and costs too much. This will only get worse if Congress simply throws yet more money at the agency.
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Beware the gatekeeper of information

Real leaders abhor secrecy like nature abhors a vacuum. Tyrants adore secrecy. Leaders don’t fear information getting out. They share it, discuss it and seek alternative points of view. This is a sign of confidence and strength. It is not a sign of weakness.

Editor's Focus

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Getting personal about personal genetics

I often feel that I have one of the most interesting and gratifying jobs a person can have—reporting on the latest life science breakthroughs and pharmaceutical discoveries, advances that may impact the bottom line of large pharmas and small biotechs right now, but will have significant, potentially life-altering, meaning for all of us later. Once in a while, a story hits especially close to home, and I can’t help but cast my red pen aside and view it from the perspective of a patient.

Automation & Instrumentation

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One bird with two stones

Agilent establishes two collaborations that continue its goal to find strong partners who can help it bring novel and effective solutions to researchers
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Double-teaming for twice the productivity

Applied Biosystems, MDS Analytical Technologies double mass spec throughput to speed drug development
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Systematic knockdown

PMCC expands cancer research efforts with Caliper's automation tool
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PerkinElmer gets chance to work with a ‘legend’

PerkinElmer, BioLegend announce custom immunoassay development collaboration for drug discovery research
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Duplicating their results

Thermo Fisher announces biomarker assay collaboration between BRIMS Center and NextGen Sciences

Feature

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What’s in a name? IBC gives DDT event a huge facelift this year and moves away from a tech overview mentality

IBC gives DDT event a huge facelift this year and moves away from a tech overview mentality
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