January 2013 Volume 9, Issue 1
Volume 9, Issue 1 | January 2013
January 2013
In this Issue
Government Watch
Coming around again with gene patents
Supreme Court to hear case challenging patents on breast and ovarian cancer genesSecond Circuit Court of Appeals rules on Caronia
First Amendment protects free speech even when promoting misbranded, off-label drug useWill FDA ‘reboot’ antibiotic approval process?
At November hearing, FDA committee approves treatment for nosocomial pneumonia, sparking debate about agency’s approval of new antibioticsResearch & Development
Selecta, Sanofi partnership nothing to sneeze at
Deal could total up to $300 million each for up to three candidatesNew CoMMpass bearings
Landmark multiple myeloma study takes on Department of Veterans Affairs as valuable new public partnerSecondhand stem cell sale
Geron announces intent to sell discontinued stem cell programs to BioTimeWhat was old is new again
Roche-Broad Institute collaboration aims to use modern platforms to find new indications for terminated development-stage compoundsFor the love of a child
Shire, Boston Children’s Hospital partner on treatments for rare pediatric diseasesSarepta Therapeutics, UCL partner on DMD drug target
Sarepta Therapeutics announced last month a collaboration with University College London for the development of an exon-skipping drug targeting exon 53, its fourth drug in development, in support of Sarepta’s broad-based program for the treatment of Duchenne muscular dystrophy (DMD)Tools & Technology
Making trials less of a trial
Janssen Research & Development announces establishment of databank to enhance global cross-pharmaceutical clinical trial effortsDuet with ALK and FISH
Abbott Molecular adopts BioView’s Duet cell imaging software for its automated Vysis ALK FISH Probe testGetting predictive with bioisosteres
Optibrium and Digital Chemistry announce technology collaboration to guide successful drug discoveryGetting PRO-ACTive about ALS
Prize4Life launches PRO-ACT ALS trials databaseA new connection with Genection
Invivoscribe launches new company to provide better, centralized genetic test offeringGlobal News
Consortium of binding interactions
K4DD helps researchers to analyze kinetics to determine drug safety and efficacy early in the development processConsortium of binding interactions
K4DD helps researchers to analyze kinetics to determine drug safety and efficacy early in the development processQC for Alzheimer’s disease
Evotec collaborates with Probiodrug on glutaminyl cyclase (QC) inhibitorsCombating cancer across the pond
Lorus, Cancer Research UK partner to advance solid tumor therapy to clinicTaking it to the tumors
Ablynx and Algeta explore combination of thorium-227 alpha-pharmaceutical and Nanobody technologyCommentary
The need for improved half-life extension technologies
In recent years, significant work has been dedicated to studying the half-life of drugs, and while researchers have been successful in lengthening the half-life of proteins and peptides, they have yet to find a way to tailor the pharmacokinetics of certain drugs to specific medical needs.”Out of Order: Out of the Mayan pan
For everyone’s sakes, we have to stay on the ball and be ready to jump in and lend a helping hand at any moment. The microbes don’t really care who we are or where we live.Editor's Focus
Three resolutions to improve your business in ‘13
If you want minimal results, resolve to do the bare minimum. If you want surprising results--results that set tongues to wagging and produce spikes in your stock price--you’ll need to think "outside of the box."Special Reports
No vaccine is an island
Adjuvant advances, international interactions and personalized preventions are transforming the world of vaccinologyOmics & Systems Biology
A game-changer in toxicity testing
Hamner Institutes’ Integrated Biology Initiative aims to fundamentally transform chemical risk assessmentTens, not thousands
Planned Stanford genomics center receives final go-aheadA ‘crucial’ partnership
Empire Genomics, Emory University to develop multiple myeloma molecular diagnosticDifferent genetic fingerprint
Researchers study microbial DNA variation in the gut for clues to healthDNA2.0 partners with Newcastle U on B. subtillis system
DNA2.0 last month announced a collaboration with Newcastle University to develop a protein expression system for Bacillus subtillisDiagnostics
Catching something in China
PerkinElmer acquires China-based infectious disease diagnostics company Shanghai Haoyuan BiotechThe sooner the diagnosis, the better the outcome
Boston Children’s Hospital develops new blood test for early diagnosis of autismHighly personalized medicine
Galena and Leica develop companion diagnostic for breast cancer therapeuticPROOF for FFPE samples
HTG Molecular Diagnostics and PROOF Centre partner to commercialize COPD prognostic test
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Discovering deeper insights into malaria research
Malaria continues to drive urgent research worldwide, with new therapies and tools emerging to combat the parasite’s complex lifecycle and global burden.
Accelerating RNA therapeutic testing with liver microphysiological platforms
Researchers can now study oligonucleotide delivery and efficacy in a system that models a real human liver.
Shining light on the subcellular proteome
Discover how innovative proteomics tools help researchers peer into once inaccessible organelles, allowing for new targets for drug discovery and development.
