January 2010 Volume 6, Issue 1

Volume 6, Issue 1 | January 2010

January 2010

In this Issue

Instruments & Informatics

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Forest preserve

Acquisition of Protein Forest gives Cell Biosciences extra proteomic muscle
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NEXUS Biosystems acquires sister company Aurora Biotechnologies

With private equity firm Telegraph Hill Partners (THP) acting as the honest broker, NEXUS Biosystems Inc. announced in December its acquisition of Aurora Biotechnologies.
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Going out on a LIMS

Millipore’s CRO unit implements Thermo Fisher Scientific’s Watson LIMS for information management
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Sequencing an alliance

Ambry Genetics, SoftGenetics form partnership for extended bioinformatics support for next-generation sequencing projects

Omics & Systems Biology

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Cancer's Grand Central Station

Merrimack Pharmaceuticals acquires Hermes Biosciences in deal to develop systems biology-driven therapeutics for cancer
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Tiny RNA; big results

Yale and Mirna researchers show that microRNAs can shrink lung tumors
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Capturing it all

Kimmel Cancer Center to study genomics using febit’s sequence capture and microRNA solutions
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Crossing their Ts

Bioo Therapeutics, Texas Tech researchers team up on targeted delivery of siRNA into T cells
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Thermo Fisher Scientific, Expression Pathology to improve identification of cancer-related proteins

Thermo Fisher Scientific Inc. also announced in December a collaboration between its Biomarker Research Initiatives in Mass Spectrometry (BRIMS) Center and Expression Pathology Inc.

Research & Development

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Celgene goes for Gloucester

Companies to merge in $340 million cancer drug deal
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The power of positive partnering

AstraZeneca, Targacept to design nicotine channel blocker TC-5214 for treatment of major depressive disorder
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The art of the cell

ImmunoCellular Therapeutics enters into option agreement with the M.D. Anderson for a novel cancer stem cell therapy
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Giving stem cell research a boost

Millipore sponsors three academic memberships for GeneGo’s MetaMiner Stem Cell project
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Tranzyme MATCHes up with Bristol-Myers Squibb

Companies pair up to develop novel macrocyclic compounds for multiple disease targets

Diagnostics

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You ought to be in pictures

IBM grant allows University of Pittsburgh researchers to use high-powered in silico modeling techniques
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Minding their assays

Rules-Based Medicine strikes diagnostic immunoassay deal with Roche through Psynova Neurotech subsidiary
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Some California dreamin’

Matrix Sensors, C3-Jian to develop microchip diagnostics based on engineered peptides
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Bruker provides a green solution for Synlab association

Spectrometry-based molecular microbial identification reduces biochemical wastes

Government Watch

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The ripple effect

Whatever shape healthcare reform takes, its impact will be felt industry-wide
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Time has nothing to show

GAO follow-up report casts shadow on FDA's post-market safety efforts
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Stem cell research funding debate hits the states

Missouri legislator proposes constitutional change aimed at banning public dollars for stem cell research
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No such thing as a free lunch in Jersey

New Jersey attorney general proposes regulations on doctors, pharma companies
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Pfizer, Lilly and Bayer fined for price-fixing in Switzerland

he Swiss branches of Pfizer Inc., Eli Lilly & Co. and Bayer AG were fined a total of $5.7 million by competition regulators on Dec. 1 for alleged price-fixing of drugs for erectile dysfunction.
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White House directive calls for open access to research publications

President Barack Obama on Dec. 8 issued a directive specifying actions that should be taken to make government agencies better able to engage with the public, including plans to make data and information from federally funded research available for public access.

Commentary

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Guest commentary: Bioinformatics research enables better biological information

With life sciences evolving so quickly, bioinformatics research is critical to building information infrastructures that can match that evolution, allow researchers to access data quickly and easily and develop new informatics tools as needed. It is no longer enough to generate the best measurement data; researchers also require the best meaning and insight from that data.
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A disappointing end to a disappointing decade

We just left behind both a year and a decade, and pundits can’t resist opining on what happened. We had few good days early in this millennium, but we’ve got 990 years to make up for it.

Editor's Focus

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Government’s watchful eye has pharma on guard

Beginning this issue, our Government Watch section will profile some of the latest legal, legislative, and regulatory developments in the pharma/biotech arenas. In our first month of coverage, we had a veritable grab-bag of stories to sink our teeth into, and settled on a wide range of topics to show our readers the various forms government scrutiny can take: federal oversight, state legislation, state regulation and international regulation, to name a few. Our writers—who are no strangers to reporting on such matters—were eager to hit the ground running and delve into these topics, but were met with an all-too-familiar roadblock: Fear.

Global News

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Opening the door to the Orient

Pfizer, Crown Bioscience in collaboration to treat cancers in Asia
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No more nosocomial infection

Novel approach to fighting hospital-acquired infections teams sanofi-aventis and U.S biotech Alopexx
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Meeting a dual need

Caliper partners with Prestwick to offer custom chemistry and biology programs for drug discovery
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Almac Clinical Technologies goes with a PRO

Ireland-based company names FACIT.org as partner for electronic distribution of patient-reported outcomes
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Fluxion expands into Asia with first China sale, distributors in Korea and Japan

Fluxion Biosciences, a provider of cellular analysis tools for use in life science research and drug discovery applications, announced in December the expansion of its sales and service network into Asia.

New Products

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Enhanced collection and storage of preclinical and clinical study samples

GE Healthcare has launched FTA DMPK cards for the collection and storage of blood samples for use in pharmacokinetic and toxicokinetic (PK/TK) studies.
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Comfortable, easy-to-use pipette reduces the risk of repetitive strain injury

Thermo Fisher Scientific Inc. has launched the Thermo Scientific Finnpipette F2 with an upgraded soft-touch tip ejector for increased ergonomics.
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Hybrid microplate reader

BioTek Instruments Inc. has expanded its Synergy Multi-Mode Microplate Reader family with the introduction of the patent-pending Synergy H4 with Hybrid Technology.

News Briefs

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PREVIEW: ALA brings even more new offerings to LabAutomation2010

ALA brings even more new offerings to LabAutomation2010 in Palm Springs, to advance knowledge among all types of laboratory professionals at all levels
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Driving gene therapy with nonviral vectors 

Learn why nonviral vectors are on the rise in gene therapy development.
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Milestone: Leapfrogging to quantitative, high throughput protein detection and analysis

Researchers continuously push the boundaries of what’s possible with protein analysis tools.
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Advancing immuno-oncology research with cellular assays

Explore critical insights into immunogenicity and immunotoxicity assays for cancer therapies.
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