February 2019- Volume 15, Issue 2

In this Issue

Preclinical

Q BioMed partners with SRI International

Q BioMed partners with SRI International

Collaboration provides Q BioMed with formulation and preclinical expertise to progress QBM-001 for pediatric nonverbal disorder in autism

Wasp venom shows potential as an antibiotic

Wasp venom shows potential as an antibiotic

Altered peptides from the venom can kill bacteria but are nontoxic to human cells

It’s all in the presentation

It’s all in the presentation

A roundup of recent preclinical data presentations

Synthetic gene promoter targets hemophilia

Synthetic gene promoter targets hemophilia

Novel approach appears to circumvent inhibitors to factor VIII in early clinical studies

Clinical Trials

Data support SYNB1020 in cirrhosis

Data support SYNB1020 in cirrhosis

Phase 1 clinical trial of SYNB1020 in healthy volunteers demonstrated safety, clearance and proof of mechanism

A new force against cancer

A new force against cancer

Nanobiotix and MD Anderson Cancer Center collaborate on new product

A guy thing

A guy thing

Simple, reversible male contraceptive minimizes side effects

Breast case scenarios

Breast case scenarios

Atossa’s male Phase 1 study of Endoxifen for breast health starts well; Phase 2 for women with MBD continues

The trials of AI

The trials of AI

Machine learning and other tools seeing increased interest for clinical studies

Diagnostics

Non-invasive options for NASH

Non-invasive options for NASH

GENFIT and LabCorp team up in licensing agreement for a NASH diagnostic test

A breath of fresh (diagnostic) air

A breath of fresh (diagnostic) air

PAN Cancer trial launches to evaluate Owlstone Medical’s Breath Biopsy platform for cancer diagnosis

Machine learning could aid sepsis care

Machine learning could aid sepsis care

Model predicts whether patients need a change in therapy

Stopping the silent killer

Stopping the silent killer

New liquid biopsy technique a powerful diagnostic tool for early detection of ovarian, endometrial cancer

Business & Government Policy

Lilly to acquire Loxo for $8B

Lilly to acquire Loxo for $8B

Among other benefits, addition of Loxo will broaden scope of Lilly’s oncology portfolio into precision medicines

On the cutting edge

On the cutting edge

A roundup of instrumentation, software and other tools and technology news

Eye on the FDA

Eye on the FDA

Agency launches new digital tool

When giants collide

When giants collide

Bristol-Myers Squibb aims to acquire Celgene for a hefty $74 billion

Contract Services

Biotech boost

Biotech boost

Dedicated PAREXEL division helps emerging companies

Imaging initiative

Imaging initiative

RadMD, AG Mednet combine specialties to offer new imaging support for clinical trials

Shore invests $6M in healthcare AI data startup

Shore invests $6M in healthcare AI data startup

H1 says it is the first to arm biopharmas with live data insights

Commentary

Revisiting the approach to Y2K, looking out to Y2K+20

Revisiting the approach to Y2K, looking out to Y2K+20

We have seen information technology anxiety run rampant in the past (with Y2K); today's worries about cyber security, fake news, autonomous robotics and artificial intelligence are nothing new...but they are worth noting nonetheless

Guest Commentary: Opportunities for personalized cancer immunotherapy directed by immune-profiling

Guest Commentary: Opportunities for personalized cancer immunotherapy directed by immune-profiling

There are currently three main approaches to characterizing the immune landscape of solid tumors: transcriptional profiling, single-cell cytometric analyses and histology; each of these disciplines brings its own benefits and, with rapid technological advances, powerful datasets are now achievable.

Discovery

Gilead and Scholar Rock target fibrosis

Gilead and Scholar Rock target fibrosis

The partners will focus on the potential of TGFβ inhibitors

Free resource against infections

Free resource against infections

New data intended to ‘spark’ much-needed antibiotic research

Cryptographic protocol aids collaboration in drug discovery

Cryptographic protocol aids collaboration in drug discovery

Neural network that securely finds potential drugs could encourage large-scale pooling of sensitive data

XtalPi to accelerate platform development

XtalPi to accelerate platform development

Closing of $46-million Series B-1 extension will aid access to AI tools

RBBP6 may hold the key

RBBP6 may hold the key

Insight into how Ebola, Dengue and Zika viruses interact with human cells opens the door for treatments

Research & Development

Amping up AMPK research

Amping up AMPK research

New model lets scientists activate health-promoting enzyme AMPK at any time, in any tissue

Blocking out genetic noise

Blocking out genetic noise

Team trains computing program to filter out benign variants to better identify pathogenic mutations

Elsevier launches Entellect

Elsevier launches Entellect

New platform designed to unlock value by creating AI-ready life-sciences data

Feature

Society of Toxicology 2019 Show Preview: Baltimore-bound for toxicology

Society of Toxicology 2019 Show Preview: Baltimore-bound for toxicology

Annual meeting and ToxExpo to unite over 300 toxicology-related companies and organizations, with more than 6,000 attendees over three da

Editor's Focus

Editor's Focus: Your 2019 intelligence briefing

Editor's Focus: Your 2019 intelligence briefing

Well, if nothing else, artificial intelligence may be about to surpass the intelligence of many of today's politicians; let's talk a little bit about both
Subscribe to our eNewsletters

Stay connected with all the latest DDN news!

Latest Issue's Magazine Cover

Latest Issue  

• Volume 17 • Issue 9 • September 2021

September 2021

September 2021 Issue