December 2020/January 2021- Volume 17, Issue 1
In this Issue
Editor's Focus
Out of order: A season of hope
Out of order: A season of hope
Sharing insights, stories, progress, and hope on fighting infectious diseases
Commentary
Goodbye DDNews; hello DDN
Goodbye DDNews; hello DDN
With our first issue of 2021, we have lots of great changes to bring you
The easy way in
The easy way in
Wide adoption and regimen compliance are two reasons for easier administration, whether with COVID or schizophrenia
Special Reports
Beyond Vaccines
Beyond Vaccines
Researchers are seeking antivirals to protect the unprotected
Discovery
Bugs making drugs: Harnessing bacteria to treat disease
Bugs making drugs: Harnessing bacteria to treat disease
Bacteria engineered to produce therapeutics fill a niche for patients with unmet medical needs.
Choosing CRISPR in the fight against SARS-CoV-2
Choosing CRISPR in the fight against SARS-CoV-2
Study demonstrates how changes in human genes can reduce SARS-CoV-2 infection
Arming the industry to fight AMR
Arming the industry to fight AMR
The AMR Action Fund seeks to support antibiotic candidates in massive industry-philanthropic alliance
Getting answers on GABAergic neurons
Getting answers on GABAergic neurons
UTSA researchers find breakthrough discovery on brain cortex functionality
Braking macrophages
Braking macrophages
Molecule mimics naturally occurring protein to prevent overreaction
Preclinical
Passage makes progress against rare lysosomal storage disease
Passage makes progress against rare lysosomal storage disease
Preclinical data show injection of optimized AAV vector may correct gangliosidosis
Deep learning for drug design
Deep learning for drug design
Metabolite Translator assesses safety of novel compounds
Exosomes to the rescue in cancer
Exosomes to the rescue in cancer
Codiak demonstrates potential of engineered exosomes to stimulate targeted, antitumor immunity
Good news for PolyPEPI-SCoV-2
Good news for PolyPEPI-SCoV-2
PepTC reports positive preclinical results for peptide vaccine
Clinical Trials
Putting RWD and NHD up against placebo
Putting RWD and NHD up against placebo
Results from cTAP indicate both could augment or replace placebo controls in DMD clinical trials
Good news to wake up to
Good news to wake up to
Jazz reports promising results for Xywav in adults with rare sleep disorder
Atossa shares Phase 1 results for AT-301
Atossa shares Phase 1 results for AT-301
Preliminary results show safety and tolerability of AT-301 nasal spray for COVID-19
Psoriasis progress
Psoriasis progress
EDP1815 Phase 1b data shared at EADV Virtual
Diagnostics
Tracing cancer with tattoo ink
Tracing cancer with tattoo ink
USC researchers say tattoo inks and food dyes could help improve cancer detection
Heavy lifting with HULLK
Heavy lifting with HULLK
APIS, University of Virginia hope to leverage HULLK lncRNA as a prostate cancer biomarker
Five minutes, one answer
Five minutes, one answer
A breath test to rapidly diagnose COVID-19 infection may be on the way from imec
Functional MRI: The next tool for mental health?
Functional MRI: The next tool for mental health?
Researchers develop an algorithm for predicting medication response in mental health patients
Feature
SLAS prepares for digital event to “Ignite 2021 with a spark”
SLAS prepares for digital event to “Ignite 2021 with a spark”
Get a look at what the Society for Laboratory Automation and Screening’s virtual annual meeting has to offer
Tools & Technology
Reaction rules
Reaction rules
Retrosynthesis tool automates molecule making
Machine learning improves tandem MS
Machine learning improves tandem MS
Purdue researchers apply machine learning concepts to create a new mass spec method
Q&A: A jump to the next step in sequencing
Q&A: A jump to the next step in sequencing
Jumpcode details how its CRISPRclean tech unites NGS and CRISPR/Cas editing
