December 2019 Volume 15, Issue 12
Volume 15, Issue 12 | December 2019
December 2019
In this Issue
Research & Development
Dragonfly Therapeutics collaborates with AbbVie
Dragonfly and its TriNKET platform to develop drug candidates for autoimmune disorders and oncology; AbbVie will have exclusive options to license some of Dragonfly’s NK cell engager immunotherapiesPlectin’s biomarker role grows
University of Houston researchers find protein on cancer stem cellsModel makers
A trio of agreements expands industry work in disease and organ modelingSpecial Reports
Special Report on Liver Disease: The phantom menace
In NASH, researchers battle a largely invisible threat, and in this feature you will get a look into how they are trying to overcome the challenges of thatFeature
SLAS 2020 Show Preview: SLAS in the sun
The Society for Laboratory Automation and Screening heads to San Diego for SLAS 2020Cancer Research News Focus Feature: Oncology--Stem to stern
A look at gastroesophageal, gastric and colorectal cancer progress, as well as other recent news of oncology research breakthroughsCommentary
Publishers’ commentary: A peek into the future
The publishers of DDNews give you a look at special features in store for the coming calendar yearEverything is too expensive
Drug prices may be too expensive, but some of the answers being touted might not be the best ones, says DDNews columnist Peter Kissinger, who shares some of his thoughts of the pros and cons of various notionsPreclinical
Printing vascularized skin
Researchers have developed a way to 3D print vascularized, living skinA step forward with MultiTEP
Alzheimer’s vaccine targeted against pathological Tau protein generates significant antibodies in miceThe immune reset
New data from Magenta Therapeutics support CD45-ADC in its ability to rebuild the immune systemCompugen presents preclinical data for COM902
Data support potential clinical use as a cancer immunotherapy treatmentAccelerating a novel glioma therapeutic
PhoreMost and Sentinel expand collaboration to progress PLK1 inhibitor through preclinical and IND-enabling studiesDiagnostics
Mologic, Sherlock combine forces for point-of-care tests
The companies hope to develop flexible new instrument-free diagnosticsDynamic combo
Promega, Merck team up on MSI diagnostic for use with KeytrudaBreathing easier with diagnostic options
Owlstone to contribute Breath Biopsy to 3TR to improve disease management across seven immune-mediated diseasesRecognizing diagnostic capabilities
Shuwen Biotech designated as an International Cooperation Base for Medical diagnostic technologiesDiscovery
Progressing epitranscriptomic drug candidates
Gotham Therapeutics establishes advanced oncology profiling cascade with ProQinaseSimulating success
Turbine secures seed funding to expand the potential of simulation-first drug discoveryModeling mantle cell
Researchers have created a new discovery model for mantle cell lymphomaPushing neuroscience discovery forward
Metrion Biosciences and LifeArc extend ion channel drug discovery collaborationClinical Trials
Combo shows promise
Antibody-drug conjugate for breast cancer gets good marks in HER2CLIMB top-line analysisA focus on fusions
Merus reports clinical data for patients with NRG1 fusions in their cancersCalcification control
Orphan drug focuses on calcification disorders in renal diseaseKarXT shows promise for acute psychosis in schizophrenia
Karuna Therapeutics candidate, which works on the muscarinic receptor, meets primary endpoint in Phase 2 trialContract Services
Driving drug discovery
Sygnature Discovery boosts high-throughput screening capabilitiesPPD expands capabilities in early development
Among the additions are significant neuroscience and ethno-bridging expertiseBusiness & Government Policy
Lonza commits to Cryoport
Partnership to provide fully integrated delivery solutions for handling of tissuesOn the cutting edge
A roundup of instrumentation, software and other tools and technology newsHarnessing T cells
Adaptate Biotherapeutics spins out from U.K.-based GammaDelta Therapeutics to accelerate development of therapeutic antibodies
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