December 2017 Volume 13, Issue 12
Volume 13, Issue 12 | December 2017
December 2017
In this Issue
Discovery
On the front line of aging research
Two TSRI initiatives tackle age-related diseaseNew data in war against resistance
Collaboration develops drug candidates with antibacterial activity‘More shots on goal’
Glythera and IONTAS agree on next-generation antibody-drug conjugatesTaking on liver disease
Takeda and HemoShear enter into exclusive drug discovery deal with a particular eye toward NASHCollaborating against cancer
New consortium to combine vast data stores, supercomputing and scientific expertise to ‘reinvent’ discovery process for cancer medicinesResearch & Development
Running the numbers
Mount Sinai team reports success in using mathematical model to predict patient response to immunotherapyA portal to genomic data
First-ever genomic atlas steers the way to understanding DNA traits, diseasesOrgans of interest
Agilent predicts kidney toxicity; Organovo and Viscient collaborate on liver treatmentAll-in-one injections
A new fabrication method out of MIT can deliver multiple biologics doses in one administrationTSRI explores modified DNA nucleotides
This repurposing of DNA to create new materials could have significant medical applicationsClinical Trials
An expanded collaboration on cancer
Boehringer Ingelheim and Sarah Cannon Research Institute broaden work into immuno-oncologyBig news for Exelixis’ MVP, Cabometyx
Company shares major advances for the use of cabozantinib in patients with HCC and RCCLong-term relief from psoriatic arthritis in sight
Phase 3 study on Taltz finds sustained improvements in joint pain and skin clearance in extension periodFull speed ahead
Microsoft, PAREXEL partner to develop cloud-based solutions to accelerate drug developmentTherapix advances cannabinoid pipeline
Clinical and preclinical efforts include targeting sleep apnea, pain and infectionSpecial Reports
Special Report on Animal Models of Disease: I am an animal
Non-mammalian models help personalize drug discoveryFeature
Special Focus on Cancer Research News
Featuring "Oncology vs. the supervillains," an article looking at several companies' recent news related to tackling some of the toughest cancers, plus a roundup of other cancer research news recentlyCommentary
Publishers’ commentary: What’s in store is ‘more’
The publishers of DDNews take a look back and a look forward as we wind up 2017Open access, open innovation
What did open-access once mean in scientific literature, what does it mean now and how does it all play into innovation and the future of science?Guest Commentary: Combinatorial screening and the future of therapeutics
How cell-based combinatorial cultures can improve cell bioprocessing and address future challenges in regenerative medicineContract Services
Ardena expands offerings
With acquisition of ABL, analytics and drug discovery capacity increasesOn the grow
Vetter lays the foundation for a state-of-the-art administration buildingCiToxLAB purchases new facility in Montreal
Move is designed to meet the growing demand for bioanalysis and biomarkers servicesDiagnostics
Lung cancer not just smokers’ disease
ALCMI and Inivata use liquid biopsy to study ctDNA in early-stage lung cancerBetter genetic mapping for better outcomes
Bionano’s Irys and Saphyr systems reportedly offer diagnostic breakthrough for genetic diseasesEnhancing digital pathology
Inspirata and Elsevier team to offer ExpertPath and ImmunoQuery in diagnostic cockpit and consultation portalBusiness & Government Policy
Novartis set to acquire Advanced Accelerator Applications
Novartis Oncology expertise to facilitate AAA’s ongoing development of theragnostic pipelineOn the cutting edge
A roundup of instrumentation, software and other tools and technology newsAlmac acquires BioClin Laboratories
Deal is expected to result in significant global expansion of existing analytical servicesIt’s all in the delivery
Checking out the news in drug delivery advancementsPreclinical
A heat shock to the system
Esanex presents new data on SNX-5422 at international cancer conferencePath toward non-addictive painkillers
Researchers reportedly enhance natural pain-relief chemicals without side effectsMasitinib delivers strike to Lou Gehrig’s disease
AB Science’s preclinical data show masitinib helps peripheral nervous system in ALSReplicating intellectual disability
New mouse model will help researchers determine how abnormalities in RNA processing can lead to learning and memory impairment
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