December 2010 Volume 6, Issue 12

Volume 6, Issue 12 | December 2010

December 2010

In this Issue

Global News

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MacroGenics hits winning target

Biotech firm’s DART antibody technology nabs potential $2.1 billion deal with Boehringer Ingelheim
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BMS builds bridges

Bristol-Myers Squibb taps Chinese partner to develop early-stage oncology compound
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Chinese take-out

China CDC signs agreement with Fred Hutchinson Center to address infectious disease and cancer research
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A DREAM alliance in pain management

Evotec and Apeiron Biologics build pain alliance around key molecule for pain regulation
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License to research

Compugen licenses novel oncology target to Seattle Genetics

Diagnostics

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Yin and yang

GE Healthcare acquires cancer diagnostic company Clarient Inc.
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A bio duo

bioMérieux and Biocartis sign strategic partnership in flexible molecular diagnostics
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Tripartite alliance

Quintiles, Dako and AstraZeneca aim to speed development of personalized medicine
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No fish story

UK Yorkshire Cancer Research Lab says luminous jellyfish cells help diagnose cancer

Research & Development

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Stem cell controversy rages on

Plaintiffs in case assert beliefs about embryonic stem cell research as final briefs are filed in federal lawsuit
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The shot(s) heard ’round the world

Hikma expands its global injectables business through the acquisition of Baxter Healthcare’s Multi-Source injectables business
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Mouse model message

Autism Speaks, SAGE Labs collaborate on plan to develop knockout rat models targeted toward treating autism
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Making a splash

Kadmon Pharmaceuticals, a new player in the biopharmaceutical landscape, is making deals
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True relief with sustained release

SurModics and Edge Therapeutics team up to develop sustained-release, site-specific neurological to fend off complications after subarachnoid hemorrhage
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Q&A with the stem cell case plaintiffs

Dr. James L. Sherley and Dr. Theresa Deisher share their thoughts about embryonic stem cell research and why they oppose President Obama's order to reinstate federal funding for eSC work

Commentary

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Publisher’s note: A look at the ddn’s top five stories of 2010

Out of all of our print and online news coverage, we have picked five stories that we feel illustrate some high points and show how ddn is unique in reporting industry news
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What is analytical chemistry?

We analytical chemists continue to have a variety of concerns about what we do, and those concerns vary with the context of where we do it. The argument stems from confusion over the worthiness of providing a service and whether that can ever fit our definition of science.
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New generation of sequencing technologies can replace quantitative PCR in mainstream R&D

The most powerful advance in genomics of the last five years has taken place in DNA sequencing technology. Capillary and gel-based Sanger sequencing has been superseded by new massively parallel approaches that offer several orders of magnitude greater sequencing capacity, at >500-fold reduction in cost per base.

Special Reports

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Financing the fight

Foundations are at ground zero in the battle against cancer
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Pink ribbons and yellow bracelets

The strange paradox of cancer’s persistence in the face of public optimism about progress toward a cure

Contract Services

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Off to the CRO races

Horizon Discovery acquires Hypoxium, launches Horizon Discovery Services
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Venn Life Sciences completes acquisition of DCI France

Addition expands Venn’s clinical trial management services in Europe
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Eager for the east

HUYA, Quintiles to co-develop new cancer drug sourced in China
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PPD expands investigator network in India

Large investigator site aims to provide clients with faster patient enrollment and reduced time to approval

Feature

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Bringing it together

LabAutomation2011 in Palm Springs will mark the first large gathering of members under the new SLAS banner

Instruments & Informatics

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Sequencing evolution

Roche partners with DNA Electronics to develop semiconductor-based sequencing system
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Image is everything

PerkinElmer and LinaTech to provide imaging subsystems for cancer treatment
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Lane to lane, run to run

Caliper turns to Sony Blu-ray technology for expedited microfluidics workflow
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Portal opens ways for smoother workflows

Perceptive Informatics enhances its eClinical platform with IBM technologies

Omics & Systems Biology

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Genomic sequencing gets ready to take off

1000 Genomes Project publishes analysis of pilot-phase work and prepares to launch next steps with help of companies like Affymetrix, Illumina, Life Technologies and 454 Life Sciences
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A one-in-a-thousand genome

Oppenheimer Foundation to direct sequencing of first human genome in PGP-1K Project
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Zeroing in on Huntington’s

Alnylam, Medtronic and CHDI Foundation form collaboration to advance RNAi therapeutic for Huntington’s disease
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Bonded by BORG

miRagen Therapeutics signs research, licensing agreements with University of Colorado for microRNA profiling of human heart failure
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Testing microRNAs on Horizon

Mirna Therapeutics will use Horizon Discovery’s X-MAN models to test activities of its tumor suppressor miRNAs
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