We analytical chemists continue to have a
variety of concerns about what we do, and those concerns vary with the context of where we do it. The argument stems from confusion over the worthiness of
providing a service and whether that can ever fit our definition of science.
The most powerful
advance in genomics of the last five years has taken place in DNA sequencing technology. Capillary and gel-based Sanger sequencing has been superseded by new
massively parallel approaches that offer several orders of magnitude greater sequencing capacity, at >500-fold reduction in cost per base.