December 2010- Volume 6, Issue 12

December 2010

In this Issue

Omics & Systems Biology

Genomic sequencing gets ready to take off

Genomic sequencing gets ready to take off

1000 Genomes Project publishes analysis of pilot-phase work and prepares to launch next steps with help of companies like Affymetrix, Illumina, Life Technologies and 454 Life Sciences

A one-in-a-thousand genome

A one-in-a-thousand genome

Oppenheimer Foundation to direct sequencing of first human genome in PGP-1K Project

Zeroing in on Huntington’s

Zeroing in on Huntington’s

Alnylam, Medtronic and CHDI Foundation form collaboration to advance RNAi therapeutic for Huntington’s disease

Bonded by BORG

Bonded by BORG

miRagen Therapeutics signs research, licensing agreements with University of Colorado for microRNA profiling of human heart failure

Testing microRNAs on Horizon

Testing microRNAs on Horizon

Mirna Therapeutics will use Horizon Discovery’s X-MAN models to test activities of its tumor suppressor miRNAs

Global News

A DREAM alliance in pain management

A DREAM alliance in pain management

Evotec and Apeiron Biologics build pain alliance around key molecule for pain regulation

License to research

License to research

Compugen licenses novel oncology target to Seattle Genetics

BMS builds bridges

BMS builds bridges

Bristol-Myers Squibb taps Chinese partner to develop early-stage oncology compound

Chinese take-out

Chinese take-out

China CDC signs agreement with Fred Hutchinson Center to address infectious disease and cancer research

MacroGenics hits winning target

MacroGenics hits winning target

Biotech firm’s DART antibody technology nabs potential $2.1 billion deal with Boehringer Ingelheim

Research & Development

The shot(s) heard ’round the world

The shot(s) heard ’round the world

Hikma expands its global injectables business through the acquisition of Baxter Healthcare’s Multi-Source injectables business

Mouse model message

Mouse model message

Autism Speaks, SAGE Labs collaborate on plan to develop knockout rat models targeted toward treating autism

Making a splash

Making a splash

Kadmon Pharmaceuticals, a new player in the biopharmaceutical landscape, is making deals

True relief with sustained release

True relief with sustained release

SurModics and Edge Therapeutics team up to develop sustained-release, site-specific neurological to fend off complications after subarachnoid hemorrhage

Q&A with the stem cell case plaintiffs

Q&A with the stem cell case plaintiffs

Dr. James L. Sherley and Dr. Theresa Deisher share their thoughts about embryonic stem cell research and why they oppose President Obama's order to reinstate federal funding for eSC work

Stem cell controversy rages on

Stem cell controversy rages on

Plaintiffs in case assert beliefs about embryonic stem cell research as final briefs are filed in federal lawsuit

Diagnostics

A bio duo

A bio duo

bioMérieux and Biocartis sign strategic partnership in flexible molecular diagnostics

Tripartite alliance

Tripartite alliance

Quintiles, Dako and AstraZeneca aim to speed development of personalized medicine

No fish story

No fish story

UK Yorkshire Cancer Research Lab says luminous jellyfish cells help diagnose cancer

Yin and yang

Yin and yang

GE Healthcare acquires cancer diagnostic company Clarient Inc.

Instruments & Informatics

Sequencing evolution

Sequencing evolution

Roche partners with DNA Electronics to develop semiconductor-based sequencing system

Image is everything

Image is everything

PerkinElmer and LinaTech to provide imaging subsystems for cancer treatment

Lane to lane, run to run

Lane to lane, run to run

Caliper turns to Sony Blu-ray technology for expedited microfluidics workflow

Portal opens ways for smoother workflows

Portal opens ways for smoother workflows

Perceptive Informatics enhances its eClinical platform with IBM technologies

Contract Services

Eager for the east

Eager for the east

HUYA, Quintiles to co-develop new cancer drug sourced in China

PPD expands investigator network in India

PPD expands investigator network in India

Large investigator site aims to provide clients with faster patient enrollment and reduced time to approval

Off to the CRO races

Off to the CRO races

Horizon Discovery acquires Hypoxium, launches Horizon Discovery Services

Feature

Bringing it together

Bringing it together

LabAutomation2011 in Palm Springs will mark the first large gathering of members under the new SLAS banner

Commentary

Publisher’s note: A look at the ddn’s top five stories of 2010

Publisher’s note: A look at the ddn’s top five stories of 2010

Out of all of our print and online news coverage, we have picked five stories that we feel illustrate some high points and show how ddn is unique in reporting industry news

What is analytical chemistry?

What is analytical chemistry?

We analytical chemists continue to have a variety of concerns about what we do, and those concerns vary with the context of where we do it. The argument stems from confusion over the worthiness of providing a service and whether that can ever fit our definition of science.

New generation of sequencing technologies can replace quantitative PCR in mainstream R&D

New generation of sequencing technologies can replace quantitative PCR in mainstream R&D

The most powerful advance in genomics of the last five years has taken place in DNA sequencing technology. Capillary and gel-based Sanger sequencing has been superseded by new massively parallel approaches that offer several orders of magnitude greater sequencing capacity, at >500-fold reduction in cost per base.

Special Reports

Financing the fight

Financing the fight

Foundations are at ground zero in the battle against cancer

Pink ribbons and yellow bracelets

Pink ribbons and yellow bracelets

The strange paradox of cancer’s persistence in the face of public optimism about progress toward a cure
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