August 2017- Volume 13, Issue 8

In this Issue

Diagnostics

Double-dose of CDx

Double-dose of CDx

Cancer Genetics launches companion diagnostic; Illumina announces NGS kit for CDx

Bolstering biomarker use

Bolstering biomarker use

New Avant Diagnostics CEO wants to integrate precision diagnostics to treatment

A ‘gem’ of a partnership

A ‘gem’ of a partnership

Genoptix and Bionano to use Saphyr System to develop hematologic cancer diagnostics

Preclinical

Knockout mice guide future autism therapies

Knockout mice guide future autism therapies

Shank3B mice that mimic typical autism behaviors provide a valuable research tool, according to preclinical trials

Alzheimer’s candidate off to a good start

Alzheimer’s candidate off to a good start

QR Pharma presents data at AAIC showing preclinical efficacy for Posiphen

Compugen presents COM701 combination data at ASCO

Compugen presents COM701 combination data at ASCO

Clinical advisory meeting held in preparation for COM701 clinical studies anticipated to begin next year

Taking down Zika

Taking down Zika

Inovio and TechnoVax edge closer to a functional Zika vaccine

Business & Government Policy

Elsevier launches The Hive 2017

Elsevier launches The Hive 2017

Applications for showcase of pharma and biotech startup innovation close at end of August

On the cutting edge

On the cutting edge

A roundup of instrumentation, software and other tools and technology news

Research & Development

Inhibiting varicella-zoster

Inhibiting varicella-zoster

NanoViricides drug candidates reduce extent of shingles virus infection of human skin

Expansion and partnering in stem cells

Expansion and partnering in stem cells

MilliporeSigma expands deal with Public Health England and teams with Elsevier for Reaxys

Two are better than one

Two are better than one

KaLy-Cell and CiToxLAB join forces to offer in-vitro and ex-vivo testing for hepatotoxicity and metabolism

Strategic alliance on plasmid DNA drugs extended

Strategic alliance on plasmid DNA drugs extended

Alma Bio Therapeutics and Delphi Genetics aim to rein in uncontrolled inflammation in autoimmune diseases

A polymerase-free paper

A polymerase-free paper

Quanterix, DestiNA Genomics publish study on new method for detecting liver tox biomarkers

Contract Services

Gotta catch ‘em all!

Gotta catch ‘em all!

Lonza acquires several companies in the first half of 2017

INC’s Japan presence expands with new office

INC’s Japan presence expands with new office

New office will allow for global CRO to continue to support rapid growth in Asia-Pacific’s largest pharmaceutical market

Before the trials come

Before the trials come

The Jackson Laboratory and Crown Bioscience announce global preclinical research agreement

Discovery

The match game

The match game

NCCU finds home for orphan diabetes drugs in the prevention of breast cancer

Ending the runaround with RNA

Ending the runaround with RNA

Earlham Institute and NEB tackle challenging RNA with new library prep kit

Partners in ‘ORBIT’ around glioblastoma multiforme

Partners in ‘ORBIT’ around glioblastoma multiforme

Heptares announces collaboration with NYU to seek brain cancer treatments

ProMIS identifies epitope target for ALS and dementia

ProMIS identifies epitope target for ALS and dementia

Company files patent application for novel target identified on misfolded forms of the protein TDP43

Answers for Alzheimer’s

Answers for Alzheimer’s

Risk of developing AD is linked to a network of genes associated with myeloid cells

Clinical Trials

An analgesic with ‘significant potential’

An analgesic with ‘significant potential’

Encouraging top-line results seen with CR845 pain relief trial in osteoarthritis patients

A double triple for June

A double triple for June

TG Therapeutics presents triple combination regimen data from two trials

Analyzing the microenvironment

Analyzing the microenvironment

Researchers define glioblastoma ecosystem for more effective immunotherapy trials

Moving forward on SMA

Moving forward on SMA

Cytokinetics announces baseline data from first cohort of Phase 2 trial in patients with spinal muscular atrophy

A look behind and ahead

A look behind and ahead

SCORR and Applied Clinical Trials release report on past and pending change for clinical trials

Feature

Commentary

An open letter to the biopharma community

An open letter to the biopharma community

As gender disparity continues in STEM fields, life-sciences industry leaders released an open letter to encourage gender diversity and offer guidelines for hiring practices

The amateur scientist

The amateur scientist

As knowledge becomes more available and science more complicated, the line between amateurs and experts can seem blurred; scientists are expected to have all the answers, and those answers are supposed to be simultaneously accessible and titillating

Editor's Focus

Of a mind to decode the mind

Of a mind to decode the mind

There are still many gaps in our knowledge when it comes to how the brain works, despite how many people are affected by mental image, but efforts are underway to try and close those gaps a step at a time
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