August 2017 Volume 13, Issue 8

Volume 13, Issue 8 | August 2017

August 2017

In this Issue

Research & Development

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A polymerase-free paper

Quanterix, DestiNA Genomics publish study on new method for detecting liver tox biomarkers
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Inhibiting varicella-zoster

NanoViricides drug candidates reduce extent of shingles virus infection of human skin
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Expansion and partnering in stem cells

MilliporeSigma expands deal with Public Health England and teams with Elsevier for Reaxys
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Two are better than one

KaLy-Cell and CiToxLAB join forces to offer in-vitro and ex-vivo testing for hepatotoxicity and metabolism
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Strategic alliance on plasmid DNA drugs extended

Alma Bio Therapeutics and Delphi Genetics aim to rein in uncontrolled inflammation in autoimmune diseases

Discovery

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Answers for Alzheimer’s

Risk of developing AD is linked to a network of genes associated with myeloid cells
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The match game

NCCU finds home for orphan diabetes drugs in the prevention of breast cancer
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Ending the runaround with RNA

Earlham Institute and NEB tackle challenging RNA with new library prep kit
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Partners in ‘ORBIT’ around glioblastoma multiforme

Heptares announces collaboration with NYU to seek brain cancer treatments
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ProMIS identifies epitope target for ALS and dementia

Company files patent application for novel target identified on misfolded forms of the protein TDP43

Clinical Trials

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A look behind and ahead

SCORR and Applied Clinical Trials release report on past and pending change for clinical trials
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An analgesic with ‘significant potential’

Encouraging top-line results seen with CR845 pain relief trial in osteoarthritis patients
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A double triple for June

TG Therapeutics presents triple combination regimen data from two trials
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Analyzing the microenvironment

Researchers define glioblastoma ecosystem for more effective immunotherapy trials
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Moving forward on SMA

Cytokinetics announces baseline data from first cohort of Phase 2 trial in patients with spinal muscular atrophy

Editor's Focus

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Of a mind to decode the mind

There are still many gaps in our knowledge when it comes to how the brain works, despite how many people are affected by mental image, but efforts are underway to try and close those gaps a step at a time

Commentary

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The amateur scientist

As knowledge becomes more available and science more complicated, the line between amateurs and experts can seem blurred; scientists are expected to have all the answers, and those answers are supposed to be simultaneously accessible and titillating
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An open letter to the biopharma community

As gender disparity continues in STEM fields, life-sciences industry leaders released an open letter to encourage gender diversity and offer guidelines for hiring practices

Feature

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Show Preview: A showcase for European life sciences

Annual congress seeks to bridge the worlds of science and business

Special Reports

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Special Report on StemCells/Cell Therapy: Skin in the game

Cell therapy meets gene therapy to advance dermatology

Contract Services

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Gotta catch ‘em all!

Lonza acquires several companies in the first half of 2017
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INC’s Japan presence expands with new office

New office will allow for global CRO to continue to support rapid growth in Asia-Pacific’s largest pharmaceutical market
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Before the trials come

The Jackson Laboratory and Crown Bioscience announce global preclinical research agreement

Diagnostics

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Bolstering biomarker use

New Avant Diagnostics CEO wants to integrate precision diagnostics to treatment
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A ‘gem’ of a partnership

Genoptix and Bionano to use Saphyr System to develop hematologic cancer diagnostics
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Double-dose of CDx

Cancer Genetics launches companion diagnostic; Illumina announces NGS kit for CDx

Preclinical

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Knockout mice guide future autism therapies

Shank3B mice that mimic typical autism behaviors provide a valuable research tool, according to preclinical trials
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Taking down Zika

Inovio and TechnoVax edge closer to a functional Zika vaccine
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Alzheimer’s candidate off to a good start

QR Pharma presents data at AAIC showing preclinical efficacy for Posiphen
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Compugen presents COM701 combination data at ASCO

Clinical advisory meeting held in preparation for COM701 clinical studies anticipated to begin next year

Business & Government Policy

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Elsevier launches The Hive 2017

Applications for showcase of pharma and biotech startup innovation close at end of August
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BioTek responds to Paris Climate Accord decision

Company also announces a site expansion and new product update
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On the cutting edge

A roundup of instrumentation, software and other tools and technology news
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A 3D rendering of lipid nanoparticles delivering RNA strands

Ensuring safety in lipid nanoparticle drug delivery

As lipid nanoparticles become promising drug carriers, understanding their potential genotoxic risks is crucial. 
A scientist wearing gloves handles a pipette over a petri dish and a color-coded microplate in a laboratory setting.

The unsung tools behind analytical testing success

Learn how fundamental laboratory tools like pipettes and balances support analytical precision.
A 3D rendering of motor neurons lit up with blue, purple, orange, and green coloring showing synapses against a black background.

Improving ALS research with pluripotent stem cell-derived models 

Discover new advancements in modeling amyotrophic lateral sclerosis.
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