August 2012 Volume 8, Issue 8

Volume 8, Issue 8 | August 2012

August 2012

In this Issue

Research & Development

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Surprising and sizable injection

BMS-AstraZeneca diabetes partnership gets $7- billion boost with BMS’ acquisition of Amylin Pharmaceuticals
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Collaboration targets complications

Sanofi, Joslin Diabetes Center to develop new medicines to treat diabetes and related disorders
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CoMMpass to multiple myeloma treatment

MMRF and US Oncology Research collaborate on landmark clinical study to advance personalized treatments for incurable blood cancer
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A cognitive collaboration

Roche, Seaside Therapeutics form alliance to discover, develop new drugs for fragile X syndrome, autism spectrum disorders
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A bioscaffold for heart disease repair

ADAPT technology could augment tissue repair in heart

Global News

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Valeant all smiles over OraPharma

Valeant acquires oral health company for $312 million
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Of warheads and wellness

Cancer Research Technology and ADC Therapeutics join forces on antibody-drug conjugates
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Tackling the TB epidemic

AstraZeneca, Cellworks and Wellcome Trust team up to fight drug-resistant tuberculosis
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An acquisition with some heart

Janssen-Cilag acquires CorImmun, gains heart failure drug
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MCPs for COPD and asthma

Prosonix and the Imperial College London partner on engineered multi-component particles for respiratory medicines
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GSK finalizes Human Genome Sciences acquisition for $14.25 per share in cash

The transaction values HGS at approximately $3.6 billion on an equity basis, or approximately $3 billion net of cash and debt

Omics & Systems Biology

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Hiding in plain sight

Researchers working on both sides of the Atlantic describe new influenza gene hidden among the known ones
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Discovery on demand

Merck Serono, Compugen launch company to develop predictive drug toxicity tests
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Zebrafish turn the tide in autism research

MIT researchers turn to fish models to uncover secrets of autism
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Cold Spring Harbor Lab, Pfizer partner on cancer therapy research

Collaborators aim to create next-generation short-hairpin RNA library
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Hit-to-lead

CellCentric and ZoBio enter into partnership to develop lead compounds against epigenetic drug targets

Tools & Technology

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The life science DREAM team

Seventh-annual Dialogue for Reverse Engineering Assessment and Methods (DREAM) challenge seeks informatics solutions to support translational medicine
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Tegal acquires CollabRx

Deal brings interpretive content and data analytics to genomics-based medicine
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Eyes on the Ion

Life Technologies and Boston Children's Hospital to develop optimized lab workflow based on Ion Proton Sequencer
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Stepping up to the platform

NCKU, Fujitsu ink MOU to build genomics platform
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KREATECH Diagnostics, ORIDIS Biomarkers go FISH

Companies to develop state-of-the-art REPEAT-FREE DNA-FISH assays for the oncology field
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QIAGEN to create NGS portfolio for clinical research, MDx

QIAGEN NV recently unveiled an initiative to enter the field of next-generation sequencing (NGS)

Special Reports

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SPECIAL REPORT: Regenerating interest in stem cell medicine (PART 1)

Stem cell technologies still hold potential to replace organs and tissues, but initial hype has been toned down
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SPECIAL REPORT: Regenerating interest in stem cell medicine (PART 2)

Stem cell technologies still hold potential to replace organs and tissues, but initial hype has been toned down

Commentary

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The promise of cell therapies in treating chronic diseases

With the introduction of adult stem cell therapies, we are now seeing new promise in the management and even treatment of chronic disease.
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August is back-to-school month

We’ve followed the science education debate for years, but jumping into the fray has caused us to think in new ways.

Editor's Focus

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Public misconceptions about stem cells throw a wrinkle into scientific progress

The great divide between actual science and general public perception—complicated by political controversy and ethical debate—has only grown deeper with every breakthrough or achievement in the quest to use stem cells to regenerate or repair damaged tissue, skin and organs.

Diagnostics

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Going primetime with real-time PCR

Luminex acquires GenturaDx for $50 million
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Custom-tailored therapy

Merrimack and Cancer Treatment Centers of America partner to advance translational research and individualized treatment
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Breaking the Parkinson’s bottleneck

Berg Pharma partners with Parkinson’s Institute to identify biomarkers in Parkinson’s disease
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Lilly, PrimeraDx break the ICE

Companies team up to develop companion diagnostics using PrimeraDx’s ICEPlex platform

Contract Services

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Renaissance Pharma acquires DPT, a CDMO

Pharma drawn to DPT’s contract development and manufacturing capabilities
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Solving the insoluble

Quotient Clinical and Capsugel will collaborate to accelerate early development and clinical evaluation for poorly soluble drugs
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Control issues

Bend Research and Catalent partner to provide integrated solutions for oral controlled-release technologies
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Global peptide partnership

Peptisyntha and Peptides International will collaborate to produce research-grade peptide active pharmaceutical ingredients
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