August 2010 Volume 6, Issue 8
Volume 6, Issue 8 | August 2010
August 2010
In this Issue
Global News

A pain-free alliance
Servier and Galapagos initiate strategic alliance in osteoarthritis
That’s Italian
Aptuit to acquire operations at GSK’s Medicines Research Centre in Verona
The potential of Polish science
Selvita and Orion collaborate on Alzheimer’s disease program
From the Buckeye State to Beijing
BioOhio, Beijing Pharma forge international biomedical, business partnershipCommentary

The role of nanoemulsions in vaccines, adjuvants, anti-infectives and dermatological treatments
The pharmaceutical industry continues to struggle with bringing new, commercially viable therapies to market.
Where will innovation come from?
In the early 1980s, I traveled to Berlin and to China for the first time. To reach Berlin, you flew in a PanAm DC-9 from Frankfurt, your only choice of airline and departure airport. It was a beautiful day. Crossing the border to East Germany, many things disappeared: color, highways, modern buildings and traffic. From low altitudes, it appeared that 30 to 40 years had just been lost.Editor's Focus

ddn dissects current cancer craze
Business deals and agreements associated with cancer research are plentiful these days, and this month, ddn’s editors and writers give you several examples of the latest oncology-related acquisitions, mergers and partnerships to be signed in this burgeoning area of pharmaceutical and biological research.Research & Development

Celgene reaches into deep pockets again
Enticed by tumor drug, Celgene acquires Abraxis BioScience for nearly $3 billion upfront and up to $650 million if certain goals are met
Getting under their skin
Valeant and Biovail agree to merge, creating leader in dermatology and neurology pharmaceuticals
sanofi-aventis continues R&D spending spree
French pharma acquires U.S. biopharmaceutical firm TargeGen for $75 million
Lilly acquisition blossoms
Company to pay as much as $380 million for Alnara
Fail-safe product and deal
Option agreement between Cadence Pharmaceuticals and Incline Therapeutics gives Cadence two option periods to acquire InclineInstruments & Informatics

Human genomics for the masses
Roche and IBM collaborate on nanopore-based DNA sequencing technology with eyes toward advancing personalized healthcare
Sosei to acquire Activus Pharma
Deal marks Sosei’s continued efforts to grow through non-organic means
Picking up the slack … and then some
Eurofins MWG Operon and Genomatix join forces to offer advanced NGS
Getting a signal
Promega, SignalChem to offer complete kinase solutionsOmics & Systems Biology

Multimillion miRNA deal
sanofi-aventis, Regulus form strategic alliance in microRNA therapeutics
Boosting R&D with a little M&A
Gilead Sciences acquires CGI Pharmaceuticals and adds numerous small- molecule kinase inhibitor compounds to its pipeline
A class of their own
Santaris Pharma, miRagen Therapeutics to develop microRNAs for treatment of cardiovascular disease
Pushing the limits of phosphoproteomics
Purdue University researcher patents new retrieval method that makes studying cancer proteins easier
Ariadne’s thread of connections
Bioinformatics company to collaborate in multimillion-dollar EU-based neuromuscular disease consortium to find biomarkersContract Services

Back to the future with Parkinson’s research
Michael J. Fox Foundation partners with leading CROs to develop biomarker candidates for Parkinson’s disease
Changing the channel
Milestone-driver collaboration between Essen BioScience and Nycomed boosts ion-channel drug discovery
A gem of a partnership
Emerald BioStructures, FORMA Therapeutics partner to develop treatments for lymphoma and other cancers
Going for prime time
Quintiles inks deal with University Malaya Medical Center in MalaysiaDiagnostics

TRANSCENDing a typical partnership
MIT’s Koch Institute collaborates with Ortho-McNeil-Janssen and affiliates in oncology R&D
A personal touch for cancer therapy
Aeterna Zentaris to collaborate with Almac on therapy and companion diagnostic in multiple oncology targets
Signed on the dotted line
Signature Diagnostics to use Affymetrix microarray technology for detecting and predicting progression of colorectal cancer
Rheumatoid arthritis reprise
TcLand Expression, a spinoff of Inserm Transfert, rejoins former partner to pursue RA companion diagnosticsSpecial Reports

Let’s work together
Peeling back the layers of integrated approaches to oncology research
The big picture
Multiple approaches—and ultimately, more comprehensive ones—are critical to understanding and treating cancerNew Products

Automates preparation of fragment libraries
Beckman Coulter Genomics has introduced the SPRIworks Fragment Library System II.

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