August 2010 Volume 6, Issue 8

Volume 6, Issue 8 | August 2010

August 2010

In this Issue

Global News

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A pain-free alliance

Servier and Galapagos initiate strategic alliance in osteoarthritis
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That’s Italian

Aptuit to acquire operations at GSK’s Medicines Research Centre in Verona
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The potential of Polish science

Selvita and Orion collaborate on Alzheimer’s disease program
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From the Buckeye State to Beijing

BioOhio, Beijing Pharma forge international biomedical, business partnership

Commentary

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The role of nanoemulsions in vaccines, adjuvants, anti-infectives and dermatological treatments

The pharmaceutical industry continues to struggle with bringing new, commercially viable therapies to market.
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Where will innovation come from?

In the early 1980s, I traveled to Berlin and to China for the first time. To reach Berlin, you flew in a PanAm DC-9 from Frankfurt, your only choice of airline and departure airport. It was a beautiful day. Crossing the border to East Germany, many things disappeared: color, highways, modern buildings and traffic. From low altitudes, it appeared that 30 to 40 years had just been lost.

Editor's Focus

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ddn dissects current cancer craze

Business deals and agreements associated with cancer research are plentiful these days, and this month, ddn’s editors and writers give you several examples of the latest oncology-related acquisitions, mergers and partnerships to be signed in this burgeoning area of pharmaceutical and biological research.

Research & Development

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Celgene reaches into deep pockets again

Enticed by tumor drug, Celgene acquires Abraxis BioScience for nearly $3 billion upfront and up to $650 million if certain goals are met
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Getting under their skin

Valeant and Biovail agree to merge, creating leader in dermatology and neurology pharmaceuticals
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sanofi-aventis continues R&D spending spree

French pharma acquires U.S. biopharmaceutical firm TargeGen for $75 million
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Lilly acquisition blossoms

Company to pay as much as $380 million for Alnara
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Fail-safe product and deal

Option agreement between Cadence Pharmaceuticals and Incline Therapeutics gives Cadence two option periods to acquire Incline

Instruments & Informatics

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Human genomics for the masses

Roche and IBM collaborate on nanopore-based DNA sequencing technology with eyes toward advancing personalized healthcare
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Sosei to acquire Activus Pharma

Deal marks Sosei’s continued efforts to grow through non-organic means
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Picking up the slack … and then some

Eurofins MWG Operon and Genomatix join forces to offer advanced NGS
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Getting a signal

Promega, SignalChem to offer complete kinase solutions

Omics & Systems Biology

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Multimillion miRNA deal

sanofi-aventis, Regulus form strategic alliance in microRNA therapeutics
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Boosting R&D with a little M&A

Gilead Sciences acquires CGI Pharmaceuticals and adds numerous small- molecule kinase inhibitor compounds to its pipeline
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A class of their own

Santaris Pharma, miRagen Therapeutics to develop microRNAs for treatment of cardiovascular disease
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Pushing the limits of phosphoproteomics

Purdue University researcher patents new retrieval method that makes studying cancer proteins easier
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Ariadne’s thread of connections

Bioinformatics company to collaborate in multimillion-dollar EU-based neuromuscular disease consortium to find biomarkers

Contract Services

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Back to the future with Parkinson’s research

Michael J. Fox Foundation partners with leading CROs to develop biomarker candidates for Parkinson’s disease
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Changing the channel

Milestone-driver collaboration between Essen BioScience and Nycomed boosts ion-channel drug discovery
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A gem of a partnership

Emerald BioStructures, FORMA Therapeutics partner to develop treatments for lymphoma and other cancers
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Going for prime time

Quintiles inks deal with University Malaya Medical Center in Malaysia

Diagnostics

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TRANSCENDing a typical partnership

MIT’s Koch Institute collaborates with Ortho-McNeil-Janssen and affiliates in oncology R&D
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A personal touch for cancer therapy

Aeterna Zentaris to collaborate with Almac on therapy and companion diagnostic in multiple oncology targets
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Signed on the dotted line

Signature Diagnostics to use Affymetrix microarray technology for detecting and predicting progression of colorectal cancer
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Rheumatoid arthritis reprise

TcLand Expression, a spinoff of Inserm Transfert, rejoins former partner to pursue RA companion diagnostics

Special Reports

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Let’s work together

Peeling back the layers of integrated approaches to oncology research
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The big picture

Multiple approaches—and ultimately, more comprehensive ones—are critical to understanding and treating cancer

New Products

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Automates preparation of fragment libraries

Beckman Coulter Genomics has introduced the SPRIworks Fragment Library System II.
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