August 2009 Volume 5, Issue 8

Volume 5, Issue 8 | August 2009

August 2009

In this Issue

Global News

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Failed drugs reincarnated

Israel’s Optimata, Teva join forces to develop salvaged cancer drugs
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Bolus of growth

Mylan chooses Bangalore’s Biocon as global generic biologics partner
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A flurry of activity

Shifting its focus to neurological conditions, Lundbeck acquires Danish biotech NeuronIcon and U.K.-based drugmaker LifeHealth
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Survive to thrive

CombinatoRx, Neuromed to merge in all-stock transaction
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Let it bleed

CDI reprograms blood cells into stem cells using a small volume of human blood; expands drug testing agreement with Roche
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Geron to provide stem cells to GE Healthcare

Companies to develop and commercialize cellular assay products derived from human embryonic stem cells

Informatics

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Search for pathway-level biomarkers

Agilent Foundation awards grant to UCSD to develop system for analyzing proteomics data and identifying protein-network cancer biomarkers
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A new home for SQL*LIMS

Seeking new strategic direction, Life Technologies sells laboratory information management software business to LabVantage
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TGen tapped for ‘biobank’

Luxembourg selects TGen to create biobank for storage of blood and tissue samples for scientists
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A ‘crossomics’ collaboration

Genedata AG signs multi-year bioinformatics deal with Roche subsidiary Chugai Pharmaceuticals
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Swiss success

Medidata makes important deals with two different Swiss pharma companies in a two-week period

Research & Development

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J&J's spending spree continues

Johnson & Johnson buys $1 billion stake in Elan to acquire Alzheimer's program
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They’re bonded by blood

Catalyst Biosciences, Wyeth Pharmaceuticals team up to treat hemophilia in collaboration worth up to $500 million
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Antibody partnership has eggs-cellent potential

Morphotek partners with Synageva BioPharma to develop therapeutic monoclonal antibodies
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Protein partners from opposite sides of the Pacific

California-based Maxygen and Japan-based Astellas form joint venture around protein therapies
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A merger of equals in specialty diagnostics

Viracor merges molecular diagnostic testing services with IBT Laboratories’ focus on immunology testing to create specialty diagnostics company

Automation & Instrumentation

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Blood test for Alzheimer's disease likely within 12 to 18 months

Millipore and Proteome Sciences sign licensing agreement to detect the disease in pre-symptomatic stage
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An array of advantages

Aushon’s 2470 microarray printer to provide customized solution for small-molecule screening at the Broad Institute.
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Nanos from the bottom up

Particle Sciences and Microfluidics combine to advance pharmaceutical nanotechnology
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Analytical team-up

RTS Life Science is partnering with Hall Analytical Laboratories to provide analytical services and consultancy in automation, inhaler testing
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Aiming to create the ‘disposable factory’

Sartorius Stedim Biotech partners with SAFC Biosciences to integrate filtration and liquid handling systems with cell culture media manufacturing services.

Editor's Focus

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Foreign governments feed biotechnology venture capital firms as U.S. appetite for bailouts wanes

While the suggestion that the United States government bail out venture capital firms has failed to attract support from government leaders—and would surely raise taxpayer ire—the mood is quite different overseas, according to recent media reports.

Patent News

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Senate Committee: 12 years of data exclusivity is cool

The U.S. Senate Health, Education, Labor, and Pensions (HELP) Committee voted last month in favor of a proposal by Sens. Kay Hagan (D-N.C.), Michael Enzi (R-WY) and Orrin Hatch (R-UT) to create a follow-on biologics (FOB) pathway that provides 12 years of data exclusivity for brand-name biologic drugs.

Commentary

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Guest commentary: American pathway to generic biologics approval remains undefined

As we stand at the forefront of major changes across the healthcare industry, a pathway for the approval of generic biologics will be one of the major initiatives in the government’s efforts to achieve reduced costs.

Genomics & Proteomics

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De novo gene genesis

Researchers identify primate-specific sequences in the human genome in comparative genomics study
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Sticking its feet into the pool

Alnylam joins GSK in donating intellectual property to patent pool for neglected tropical diseases
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Protein power

Celera issues licenses for five oncology targets to Bayer Schering Pharma
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Two Xs mark diagnostic spot

Exosome Diagnostics and DxS collaborate to develop blood-based tests for key cancer mutations
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High-value vaccine investment

Juvaris to use Antigen Discovery’s protein microarray screening system to discover disease-specific antigens and fuel its vaccine pipeline

News Briefs

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House vote a victory for biotechs in biosimilars battle

A House panel has approved a provision in legislation that would give biosimilar drugs 12 years of protection from competing medicines.
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