April 2011- Volume 7, Issue 4

April 2011

In this Issue

Contract Services

Fujifilm focuses on biotech future

Fujifilm focuses on biotech future

Photo media-centric firm snaps up Merck’s contract manufacturing and service subsidiaries Diosynth and MSD Billingham

Good manufacturing practice

Good manufacturing practice

Viropro acquires Alpha Biologics’ biotech GMP production facility and CRO services

A regulatory affair

A regulatory affair

Clinipace Worldwide acquires Regulus Pharmaceutical Consulting

Quality and quantity

Quality and quantity

QPS increases Asian presence, expands clinical trials with acquisition of majority stake in Taiwan-based Qualitix

Pearl of the Orient

Pearl of the Orient

Bristol-Myers Squibb’s newest ‘String of Pearls’ addition is Chinese outsourcing firm WuXi PharmaTech, which will build a stability testing facility for BMS in China

Helping a new swimmer in the biopharma pool

Helping a new swimmer in the biopharma pool

Quintiles supports Samsung’s entry into the biopharma market through joint venture and makes minority investment in Samsung biosimilars manufacturing facility

Special Reports

Drug delivery: Why getting there isn’t half the fun

Drug delivery: Why getting there isn’t half the fun

With evolving dosage forms, the dissolution test is constantly being altered

Diagnostics

Risk and reward

Risk and reward

Mira Dx licenses triple-negative breast cancer risk variant from Yale University

Test for the weary

Test for the weary

Chronix Biomedical and Hemispherx Biopharma join forces to develop diagnostic test for Chronic Fatigue Syndrome

Lightening its load

Lightening its load

Thermo Fisher Scientific sells Athena Diagnostics to Quest Diagnostics, Lancaster Laboratories to Eurofins in two deals totaling $940 million

Patient-driven, not disease-driven

Patient-driven, not disease-driven

Ipsen and bioMérieux form broad therapeutics and diagnostics alliance

A mutual interest in mutants

A mutual interest in mutants

Novartis taps Invivoscribe for test to identify FLT3- positive AML patients

Global News

Playing a blocking game against tumors

Playing a blocking game against tumors

Cancer Research Technology and Institute of Cancer Research sign discovery and development deal with ZoBio

Organizing with ORIS

Organizing with ORIS

IDBS powers personalized cancer care at King’s Health Partners with enterprise translational medicine platform

A Phenomica partnership

A Phenomica partnership

Phenotypic screening of massive peptide library to be launched by drug discovery spinoff

A future without fat?

A future without fat?

Vancouver’s Sirona Biochem to acquire France-based TFChem for technology in treating obesity, diabetes

Japanese pharmas eye opportunities abroad

Japanese pharmas eye opportunities abroad

Kyowa Hakko and Daiichi Sankyo acquisitions of foreign firms total $1.4 billion, signaling that Japanese firms are turning to international M&As for pipeline growth

Omics & Systems Biology

Being PARP of the solution

Being PARP of the solution

MDxHealth tapped by Newcastle University, Cancer Research Technology and Pfizer to help develop companion diagnostic for PARP-based ovarian and breast cancer treatment

Covance, ISB form brain tumor partnership

Covance, ISB form brain tumor partnership

Researchers to study the genetic differences occurring within glioblastoma multiforme

Cell therapy collaboration prepares to (fibro) blast off

Cell therapy collaboration prepares to (fibro) blast off

Fibrocell Science, UCLA announce collaboration aimed at fibroblast research

Calling ADAM-12

Calling ADAM-12

Gene probed by Missouri researchers shows promise for variety of hard-core offenders

British researchers locate key to early bowel cancer detection

British researchers locate key to early bowel cancer detection

Cancer Research U.K. scientists link DNA methylation patterns to deadly form of cancer

Research & Development

A Forest grows around it

A Forest grows around it

Forest Laboratories commences $1.2 billion tender offer for all outstanding shares and certain notes and warrants of Clinical Data

Finding potential cures in the ‘public library’

Finding potential cures in the ‘public library’

Scripps and MIT scientists discover class of potent anti-cancer compounds that may also lead to new therapies for Alzheimer's disease patients

No immunity for autoimmune disease

No immunity for autoimmune disease

Merck, Lycera team up to advance program that targets Th17 cells

The pulse of heart treatment

The pulse of heart treatment

Nile Therapeutics to collaborate with Medtronic on clinical development of cenderitide for heart failure and renal disease

HGS, FivePrime ink agreement to develop anti-cancer drug

HGS, FivePrime ink agreement to develop anti-cancer drug

Human Genome Sciences Inc. (HGS) and FivePrime Therapeutics Inc. announced March 16 that they have entered into an agreement to develop and commercialize FivePrime’s FP-1039 product for multiple cancers.

UMass Human Stem Cell Bank and Registry partners with U.K. Stem Cell Bank

UMass Human Stem Cell Bank and Registry partners with U.K. Stem Cell Bank

The University of Massachusetts Human Stem Cell Bank and Registry and the United Kingdom Stem Cell Bank on March 15 signed an agreement to share best practices for stem cell banking and to collaborate on standards for stem cell line characterization, production and distribution in the United States and U.K.

Coastal cancer collaboration

Coastal cancer collaboration

Gilead Sciences acquires oncology-focused biotech Calistoga Pharmaceuticals for $375 million

Instruments & Informatics

Agilent advances with acquisitions

Agilent advances with acquisitions

Seeking to further its application development and market penetration, Agilent Technologies adds BIOCIUS Life Sciences and Lab901 to its fold

Bruker acquires Michrom Bioresources

Bruker acquires Michrom Bioresources

Michrom’s nanoflow ultra-high performance liquid chromatography system is principal asset driving the deal

Teaming up to interrogate genes about ADME

Teaming up to interrogate genes about ADME

Roche and RainDance Technologies join forces in targeted sequencing to advance research into drug metabolism and response

Talkin’ ’bout my generation

Talkin’ ’bout my generation

Ingenuity Systems, Covance collaborate to support next-generation sequencing research

Building next-gen castles in the cloud

Building next-gen castles in the cloud

Geospiza and NuGEN integrate cloud-based software and sample preparation to accelerate results using next-generation sequencing

HP aims to speed drug discovery research with inkjet technology

HP aims to speed drug discovery research with inkjet technology

Technology giant Hewlett-Packard Development Co. (HP) recently released a drug research application for the company’s inkjet technology that reportedly enables pharmaceutical companies to more efficiently develop better drugs through vastly more precise dispensing of dosages.

Editor's Focus

A message for Japan: ‘Ganbare’

A message for Japan: ‘Ganbare’

Although ddn’s news coverage spans the global drug discovery industry, we don’t often have occasion to report on Asia-based companies, as they rarely pursue large-figure mergers and acquisitions.

Commentary

Too big to succeed, too entrenched to listen

Too big to succeed, too entrenched to listen

As I mentioned in a recent column, success begets failure. Individual winners become complacent or drunk with power.

Guest Commentary: What’s driving the decline in AIDS news coverage?

Guest Commentary: What’s driving the decline in AIDS news coverage?

According to a new study, media coverage of HIV/AIDS fell more than 70 percent in developed countries over the last two decades.
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