April 2009- Volume 5, Issue 4

In this Issue

Informatics

Deliver the liver

Deliver the liver

Entelos, the Hamner Institutes and FDA team up to create in silico platform for liver toxicity.

‘Parallelized’ next-gen sequencing database

‘Parallelized’ next-gen sequencing database

National Center for Genome Resources chooses Kognitio WX2 database to peer more deeply into the genome for next-gen sequencing data.

The dawn of collaborative research

The dawn of collaborative research

Arizona Biomedical Research Commission strikes deal with 5AM Solutions to develop virtual tissue bank serving bioresearchers

Cystic fibrosis research goes electronic

Cystic fibrosis research goes electronic

Cystic Fibrosis Foundation deploys Medidata Solutions’ Rave platform to manage clinical data, increase efficiency

Breaking down silos

Breaking down silos

Waters and LabVantage integrate laboratory informatics to advance data management across global organizations.

Genomics & Proteomics

Getting the signals crossed

Getting the signals crossed

A collaboration between Imperial College and GSK focused on mRNA suggests signaling problems in the brain may lead to schizophrenia.

Genome sequencing for $5,000?

Genome sequencing for $5,000?

Complete Genomics is partnering with Broad Institute to conduct human sequencing studies of cancer.

HIV primate progress

HIV primate progress

Researchers at Rockefeller University have successfully altered one gene in HIV-1 to infect monkeys with a human version of virus.

Mighty ‘mito’

Mighty ‘mito’

University of Virginia researchers may have identified a key to reversing neurodegenerative disease in investigational protein.

Clearing the air(way) in fight against CF

Clearing the air(way) in fight against CF

Researchers find that IFRD1 gene might be a key to treating cystic fibrosis lung disease.

Research & Development

Genentech, Salk find new mechanism that may lead to Alzheimer's disease

Genentech, Salk find new mechanism that may lead to Alzheimer's disease

The mechanism of action of a heretofore puzzling protein thought to play a key role in Alzheimer's disease has been unraveled by scientists at Genentech and the Salk Institute.

Putting liver on a chip

Putting liver on a chip

Battelle Ventures spins out Hepregen, commits $5 million to develop microliver platform.

Researchers close in on possible flu foe

Researchers close in on possible flu foe

Scientists identify human monoclonal antibodies to fight bird and seasonal flu viruses.

U.S. lawmakers revisit plans to approve biosimilars

U.S. lawmakers revisit plans to approve biosimilars

Congressional lawmakers recently introduced two competing bills that would create an approval process for generic biopharmaceuticals.

Merck, Schering merge in $41.1B deal

Merck, Schering merge in $41.1B deal

Increasing generic competition and pricing pressures unite two more of the world's largest pharmas

Obama brings change to stem cell arena

Obama brings change to stem cell arena

Industry reacts to executive order lifting federal funding restrictions on embryonic stem cell research

Global News

Buy and build

Buy and build

Lab21 eyes international growth with Biotec Laboratories acquisition.

Talkin' 'bout regeneration

Talkin' 'bout regeneration

Novartis and Epistem have inked a regenerative medicine R&D deal worth up to $50 million.

Cancer’s silver bullet

Cancer’s silver bullet

UK’s Argenta Discovery and PRECOS have launched a cancer drug discovery alliance.

Lean on me

Lean on me

Pharmexa and Affitech are looking to reverse merger deal to get them back on track in the antibody field.

All pharma friends again

All pharma friends again

After an initial tender offer, two refusals and a hostile takeover threat, Roche finds a price that Genentech likes

Automation & Instrumentation

Closing the gaps

Closing the gaps

Beckman Coulter acquires Olympus' Life Science business and gains comprehensive range of diagnostic capabilities.

Millipore acquires Epitome’s EpiTag assets

Millipore acquires Epitome’s EpiTag assets

Acquisition will accelerate the development of multiplex immunoassays for cell signaling.

Time-to-clinic tools

Time-to-clinic tools

GE Healthcare and Tecan will team up to streamline process development.

Bedside to bench

Bedside to bench

Gentel and Eprogen commercialize whole-proteome array technology

DDN Editorial Roundtable: Current and Emerging Trends in Automation and Detection

DDN Editorial Roundtable: Current and Emerging Trends in Automation and Detection

At ALA's LabAutomation2009, Drug Discovery News assembled an expert panel to discuss assay automation--about how their operations run, as well as some of the hurdles they face in automating assays.

Editor's Focus

Stop the presses: DDN expands online product

Stop the presses: DDN expands online product

As other publishers are finding ways to cut their services, DDN is growing and becoming more innovative in the way we reach our readers, while still maintaining our dedication to excellent news reporting. Effective this month, you will notice that we have made many changes to DDN Online and drugdiscoverynews.com to respond to our readers’ changing needs and habits.

Commentary

Patent Office budget shortfall will have long-term effects

Patent Office budget shortfall will have long-term effects

You’re not alone in your financial suffering. The recession has even hit the U.S. Patent and Trademark Office, which is funded by fees paid by applicants for patent applications and other services.

Stem cell controversy continues

Stem cell controversy continues

Despite lifted federal funding ban, new research methods and FDA approvals, social and ethical questions remain
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