Preventing autoimmune disease
Once symptoms show up, it’s too late to cure many autoimmune diseases. Researchers are investigating ways to prevent the conditions from starting at all.
Internal Medicine
Developing new drugs to treat addiction
No pharmaceutical treatments exist for addictions to drugs like cocaine or cannabis. Now, scientists are engineering gene therapies, immunotherapies, and more.
Mitochondrial transplants recover damaged kidneys
Researchers injected healthy mitochondria to acutely injured kidneys to make them viable for donation.
The Bristol Myers Squibb approach to toxicology
Clinical trial insights refine early-stage toxicology evaluations, yielding safer medicines.
Developmental and reproductive toxicology and pathology
Evaluating drug toxicity to development and reproduction is a critical component of drug safety assessment.
Healing a broken heart
After a heart attack, the damage is permanent — for now. Researchers are testing innovative ways to get the heart to regenerate muscle cells and fix itself.
Decoding the molecular complexity of biologics
Biologics like monoclonal antibodies and mRNA vaccines are complex drugs. Yongchao Su uses biophysical tools and innovative strategies to understand them better.
Personalizing nutrition based on the gut microbiome
A new metabolic model predicted short-chain fatty acid production based on an individual’s microbiome, diet, and prebiotic or probiotic input.
Detecting exposure risk from gene therapy viral vectors
Researchers created an improved method for assays that detect viral vectors in a patient’s blood or urine. It’s used to ensure that bystanders will not be exposed.
A new cell type to fight obesity
Specialized cells in omental adipose tissue may repress fat cell development.
