How heritable is the epigenome?
Isabelle Mansuy explores how life experiences alter the epigenome of an organism and its descendants.
Internal Medicine
Deadly alcoholic hepatitis finds hope in epigenetics
With a high mortality rate and no treatment, alcoholic hepatitis is a tragic diagnosis. But a new molecule that alters patient epigenetics may become the first effective therapy for the disease.
When happy accidents lead to new discoveries
No one ever hopes to mess up an experiment, but sometimes what seems like a frustrating misstep actually sparks a discovery.
Unlocking fertility’s secret recipe using lab-created cells
In a step towards understanding spermatogenesis and infertility, researchers created testicular cells that are key to sperm transport from human stem cells.
The potential placental origins of schizophrenia
Researchers identified schizophrenia risk genes that mediate placental, rather than brain, function, revealing new insight into the disease’s developmental origins.
A squirmy system for studying cancer’s spread
Researchers use fluorescence-based imaging to visualize a cellular invasion event in worms, revealing candidates for gene knockdown strategies to block metastasis.
Fishing for safer nanomedicine
To pinpoint nanomaterials that show toxic effects in biological systems, researchers rely on the petite but powerful zebrafish.
The human virome: friend, foe, or both?
Scientists have appreciated the roles of bacteria in our microbiomes for decades. Now, they’re studying the effects of the trillions of viruses that call the human body home.
Targeting T cells to fight chronic transplant rejection
Certain T cells may offer potential therapeutic targets for prolonging organ survival in kidney transplant recipients.
