Immunology

By Mel J. Yeates

OSE brings CLEC-1 to AACRR

CLEC-1 is a new therapeutic target for immuno-oncology. 
The research program focuses on developing a cancer immunotherapy targeting CLEC-1, a newly identified C-type lectin receptor, to block suppressive functions of myeloid cells and restore antitumor response to T lymphocytes. Suppressive myeloid cells have the ability to accumulate in the tumor microenvironment and deregulate the immune activation of T lymphocytes.
A Network Approach to Target Validation
By Ilene Schneider

A Network Approach to Target Validation

Walter Kolch, co-founder and director of Systems Biology Ireland discusses the merits of a network approach to target validation and why probing clinical samples early is critical to increasing drug development success.
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