| 2 min read
Register for free to listen to this article
Listen with Speechify
0:00
2:00
CAMBRIDGE, Mass.—Reminding everyone that Paris-based Big Pharma company sanofi-aventis still wants Genzyme Corp., the two companies have noted that they are now talking officially about the acquisition.

More specifically, Jan. 10 saw an official announcement from Genzyme that not only have discussions been continuing between the financial advisors for both companies for some time, but now actual representatives from both companies are involved. That news immediately sent Genzyme shares up 3 percent, which one might consider a blow to sanofi, which has stood firm on the same bid for months and refused to budge, but sources are saying the French company may not be as rigid on that point as it once was.

So, you might ask: Is Genzyme coming to a realization that no other white knight-style suitors are likely to show up or is sanofi-aventis realizing it will have to come up off the $69-per-share number it hasn't budged on so far (about $18.5 billion in total) to seal the deal?

So far, neither side has admitted to blinking, so the answer on that is hazy—though likely a little of both. However, the discussions have, according to Genzyme, "focused on potential terms for a negotiated transaction and have included the possible use of a contingent value right relating to blood cancer drug alemtuzumab [Campath, which Genzyme also wants to market as a multiple sclerosis treatment under brand name Lemtrada] as part of any potential resolution of differences with respect to value." Reuters, Bloomberg and other media sources have noted that sources close to the deal think the $69 figure is edging upward at least slightly. Those sources were also saying no hard numbers were on the table as of Jan. 10.

The commercial potential of Lemtrada is one point of contention between the companies, as is the length of time it will take to resolve some Genzyme manufacturing problems that date back to June 2009.

Theoretically, given the direction of things right now, sanofi-aventis might work out a deal structure known as a contingent value right (CVR), which would give Genzyme shareholders a chance to reap additional payouts if Campath were to be approved for multiple sclerosis and meet certain revenue targets. Genzyme thinks the Lemtrada version of alemtuzumab could hit peak annual sales of around $3.5 billion, though sources have indicated that $700 million is more what sanofi thinks is likely.

In any case, sanofi released a statement saying that there remained "significant differences on the terms and conditions of the potential CVR and the value of our offer" and added there was no guarantee they would reach an agreement.

"A CVR would appear to be the best possible solution for the two parties that would enable them to bring these talks to a satisfactory conclusion," wrote CM-CIC Securities analyst Arsene Guekam in a note about the acquisition, with Bank Sarasin analyst David Kaegi adding in his own note that a CVR would likely bring another $5 to $8 per share, depending on market approval of Lemtrada and the meeting of certain sales targets.

"Once the parties agree on this issue, sanofi may get finally access to Genzyme's books by raising its offer by an additional $1 to $2 per share," Kaegi notes. "It seems quite probable that a deal will be finally reached because no white knight has stepped up for Genzyme so far."

About the Author

Related Topics

Loading Next Article...
Loading Next Article...
Subscribe to Newsletter

Subscribe to our eNewsletters

Stay connected with all of the latest from Drug Discovery News.

Subscribe

Sponsored

A blue x-ray style image of a human body is shown with the liver illuminated in orange against a dark blue background.

Harnessing liver-on-a-chip models for drug safety

Discover how researchers leverage microphysiological systems in toxicology studies.  
A person wearing a white lab coat types on a laptop with various overlaid enlarged files shown with plus signs on file folders floating over the laptop screen with a clinical lab shown in the background in grey and white tones.

Enhancing bioanalytical studies with centralized data management

Learn how researchers can improve compliance and efficiency with advanced LIMS solutions.
A 3D-rendered digital illustration of a molecular structure floating among red blood cells in a bloodstream environment.

Explained: How are metabolite biomarkers improving drug discovery and development?

By offering a rich source of insights into disease and drugs, metabolite biomarkers are at the forefront of therapeutic exploration.
Drug Discovery News March 2025 Issue
Latest IssueVolume 21 • Issue 1 • March 2025

March 2025

March 2025 Issue

Explore this issue