Firmly planted in glyco-engineering

If biologics are ever to take hold as large-market therapeutics, it will be largely because of companies who succeed in closely mimicking the post-translational modifications found in human systems

Register for free to listen to this article
Listen with Speechify
0:00
5:00
EAST WINDSOR, N.J.—If biologics are ever to take hold as large-market therapeutics, it will be largely because of companies who succeed in closely mimicking the post-translational modifications found in human systems; modifications such as phosphorylation and glycosylation. With this in mind, Phyton Biotech announced the acquisition of a glycoprotein engineering platform from Dow Chemical. The deal is expected to enhance an existing collaboration with Dutch research group Plant Research International.
 
The company expects to use the new platform to humanize monoclonal antibodies, which has been shown elsewhere to not only improve efficacy and diminish immunogenicity, but also to improve half life. According to a 2004 report by Frost & Sullivan, glycoprotein therapeutics are the fastest growing segment in the biopharmaceuticals industry with a CAGR of 24%.
 
This excitement has been borne out in recent years with several companies jumping into the glycomics market, including Merck's acquisition of GlycoFi and Roche's acquisition of Glycart Biotechnology.
 
In the report, Frost analyst Giridhar Rao warned that production capacity would also be critical in the success of this field. Apparently heeding this warning, Phyton also announced the installation of its second 75,000-L bioreactor at the company's cell fermentation operations in Arhensburg, Germany.


Subscribe to Newsletter
Subscribe to our eNewsletters

Stay connected with all of the latest from Drug Discovery News.

DDN July 2024 Magazine Issue

Latest Issue  

• Volume 20 • Issue 4 • July 2024

July 2024

July 2024 Issue