DNA synthesis is a foundational process in biology that enables the storage, replication, and transmission of genetic information. Advances in synthetic biology have expanded this natural process beyond cellular replication, allowing researchers to create custom DNA sequences for applications ranging from molecular biology and genome engineering to cell and gene therapy development.
This article examines the biological mechanisms of DNA synthesis, the evolution of de novo DNA synthesis technologies, and the growing role of enzymatic approaches in enabling the construction of longer and more complex DNA sequences for modern biotechnology applications.
Download this article to learn:
- The differences between template-dependent DNA replication and de novo DNA synthesis
- How chemical and enzymatic DNA synthesis technologies work and their respective strengths and limitations
- Current and emerging applications of synthetic DNA in genome editing, diagnostics, and drug discovery
