Neuroscience
| 3 min read
Activating specific neurons using light helped scientists establish a causal link between improved sleep and diminished signs of Alzheimer’s disease in mice.
| 5 min read
By masking ketamine from placebo for the first time, researchers reveal the importance of accounting for expectancy in trials testing psychoactive drugs.
| 10+ min read
Cancer anywhere in the body can change brain activity, and brain activity can drive cancer growth. These surprising discoveries are leading to new treatments.
| 4 min read
A new porcine model for the rare neurological disorder CLN3 Batten disease more faithfully recreates human symptoms and could accelerate drug development.
Available on Demand
Slight modifications to glycoproteins reveal critical insights into disease onset, state, and progression, making them a wellspring for biomarker discovery.
| 4 min read
Researchers identified a peptide that selectively blocks pain signaling in sensory neurons and packaged it into a viral-based gene therapy in a step towards treating chronic pain without the risk for addiction.
| 4 min read
Although harmful in large quantities, hydrogen sulfide may ameliorate the health consequences of aging when small doses are applied to the mitochondria.
| 3 min read
An allosteric inhibitor may block glutamate’s toxic effects in the brain without affecting healthy synaptic neurotransmission.
The blood-brain barrier seems impenetrable, but new therapeutic antibodies may creep past its defenses.
| 3 min read
A small molecule called ALGERNON2 improved health outcomes in mouse models of neurodegenerative diseases by activating antioxidant pathways in astrocytes.
| 6 min read
With ongoing advances, NMR spectroscopy remains a unique tool for unraveling the structural secrets of proteins.
| 9 min read
Molecules that promote restoration of the neuron’s myelin sheath could offer a reparative therapy for multiple sclerosis.
