Infectious Disease & Vaccines

A new mechanism for inhibiting membrane proteins could pave the way for more effective antibiotics.

Some infectious diseases require unique modifications to the traditional vaccine development approach.  

Pathogens invade mucosal surfaces like the nose, but typical vaccines don't mount an immune response there. Newly engineered mucosal vaccines, however, do.

Epithelial cells partner with tissue-resident memory cells to protect the lung during Streptococcus pneumoniae infection.

Inhibiting an enzyme variant that contributes to severe COVID-19 in men holds promise for treating SARS-CoV-2 infections. 

No one ever hopes to mess up an experiment, but sometimes what seems like a frustrating misstep actually sparks a discovery.

Researchers developed ingestible capsules that inject drugs into the stomach and small intestine, providing a novel oral delivery method for biologics.

Scientists have appreciated the roles of bacteria in our microbiomes for decades. Now, they’re studying the effects of the trillions of viruses that call the human body home.

Mireille Kamariza develops new chemistry-driven diagnostics for tuberculosis that can reduce the time to treatment from weeks to minutes.

Katalin Karikó and Drew Weissman received this year’s Physiology or Medicine award for their work on RNA biology and mRNA-based vaccines.

For decades, researchers have tried to craft a successful vaccine for HIV. mRNA vaccines may offer the answer.

Chagas disease stems from a parasitic infection. Now, with the help of a few insect-eating monkeys, a new treatment for this condition is on the horizon.