Immunology

Using a machine learning approach, researchers discovered how to make mouse macrophages resistant to tuberculosis infection.

As bispecific antibodies emerge as therapeutic game changers, scientists leverage cutting-edge technologies to navigate their multifaceted development.

Natural killer cells offer safe and effective cancer treatment, but to succeed in the clinic, they need a bit of an energy boost.

Immunologist Gabriel Rabinovich leverages his 30 years of experience studying sugar-binding proteins, galectins, for developing novel therapies.

Molecules that promote restoration of the neuron’s myelin sheath could offer a reparative therapy for multiple sclerosis.

Pathogens invade mucosal surfaces like the nose, but typical vaccines don't mount an immune response there. Newly engineered mucosal vaccines, however, do.

Epithelial cells partner with tissue-resident memory cells to protect the lung during Streptococcus pneumoniae infection.

Antibodies that simultaneously target two distinct antigens overcome cancer therapy resistance by addressing antigenic diversity and diminished T cell action. 

Different precision medicine approaches modulate distinct pathways to treat cancer, but how do scientists know which approach is best?

Technological breakthroughs and innovative strategies are propelling the ongoing evolution of CAR T cell therapy. 

Screening 12,000 genes helped researchers develop new generation CAR T cells for cancer therapy.

Scientists developed hypoimmune induced pluripotent stem cells to reduce the risk of immune rejection and immunogenicity during cell therapy.