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Hematology

| 3 min read
Building off some earlier, promising research, a team of researchers at the National Cancer Institute (NCI) of the National Institutes of Health have found that the drug vorinostat, a histone deactylase inhibitor, may be able to cross the blood-brain barrier and stave off brain metastases—something that may be particularly welcome news to breast cancer patients.

| 3 min read
Virginia Commonwealth University researchers recently announced they have identified a gene that may play a key role in regulating tumor progression in neuroblastoma, a form of cancer usually found in young children. This particular culprit—and potential lead on developing a therapy to inhibit the expression of this gene—turns out to astrocyte elevated gene-1 (AEG-1).

| 2 min read
Researchers at the University of North Carolina at Chapel Hill School of Medicine and UNC Lineberger Comprehensive Cancer Center have found that defects in a gene called p18 prevents tumor-suppressor genes from controlling healthy cell proliferation, leading to cancer. According to the researchers, their discovery may lead to new test treatments for luminal-type tumors, which account for between 70 and 80 percent of all breast cancers.




