Research Areas
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Abbott and Dharmacon Inc. have entered into a collaboration to develop new therapeutic agents based on RNAi.
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Dana Farber Cancer Institute (DFCI), 454 Life Sciences and other research centers performed detailed sequencing experiments to identify subtle but significant cancer-associated mutations.
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Metabolex announced a strategic agreement with Ortho-McNeil to collaborate on the development and commercialization of compounds targeting metabolic disorders.
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Because of their pivotal role in so many cell growth functions, microtubules are popular targets for anti-cancer drugs. Unfortunately, drug resistance and toxicity can be significant problems.
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In cancer treatment, the correlation of pharmacogenomics and drug efficacy requires genetic sampling directly from tumors, but this presents difficulties in terms of invasiveness and sample preparation.
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Multimedia
Explore how direct cell lysis can reduce sample preparation steps and support efficient gene expression analysis by RT-qPCR.
Explore how cereblon allostery and cellular target engagement profiling can reveal the mechanisms and selectivity underlying degrader activity.
