Cancer Research

Scientists discovered a long sought-after inhibitor for the DNA repair polymerase, Polθ, which may be key to treating drug-resistant BRCA1 and BRCA2-mutant cancers.

Classical model systems such as cell culture and mice are key to understanding cancer. But what can we learn by examining how cancer works in other models? Animals like naked mole rats and Tasmanian devils offer a new perspective on how cancer works and how we can treat it.

A new molecule in Phase 1 clinical trials kills leukemia cells by blocking their ability to repair DNA.

Epidemiologists may have found the perfect method to delineate if long-term use of antihypertensive medications increases cancer risk.

Using a mouse model of breast cancer brain metastasis, researchers showed that tumor cells require fatty acid synthesis to grow, which offers a potential therapeutic target.

A special report on cancer. The work led to a better understanding of the roles of tertiary lymphoid structures in cancer and its response to immunotherapy.

“A large number of pipeline agents with innovative approaches are under investigation for adjuvant, intermediate, and advanced therapy [for hepatocellular carcinoma].” Mandana Emamzadeh of GlobalData

Pyxis Oncology closes $152-million Series B financing to further advance portfolio

Bright Peak Therapeutics and Ajinomoto enter into research collaboration for novel immunocytokines

Twist Bioscience launches NGS methylation detection system for cancer analysis and epigenetic studies