With videos of dramatic cancer cell deaths and unflagging T cell attacks, Alex Ritter studies how immune cells and tumors battle with microscopic precision.
Researchers discovered that copper induces cytotoxicity through a distinct pathway termed cuproptosis. This insight guides the use of copper-shuttling drugs to treat copper regulation disorders and opens up new therapeutic applications for cancer.
While some pediatric brain cancers have known genetic causes, many do not. Three-dimensional profiling revealed new disease mechanisms and drug targets.
CAR T cell therapies use engineered T cells to fight cancer, but they can sometimes cause neurotoxic side effects. Herpes virus reactivation in donor CAR T cells may be to blame.
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