DDN Content Team

Articles by DDN Content Team

A group of drug discovery scientists reviews a grid of four distinct tissue-derived images representing different emerging spatial biology applications.
| 5 min read
Side-by-side comparison of a 5-liter bench-scale bioreactor and a 2,000-liter production-scale single-use bioreactor, illustrating the engineering challenge of scale-up across three orders of magnitude.
| 7 min read
A GMP single-use biomanufacturing suite with single-use bioreactor platforms, organized tubing assemblies, and gowned operators, showing a fully disposable facility design with no stainless steel vessels.
| 8 min read
A modern GMP biopharmaceutical manufacturing facility with rows of single-use bioreactors and process automation systems, with gowned technicians monitoring real-time production data.
| 10+ min read
A conceptual illustration of a fragile supply chain made of ice containers linked by glowing chains, transporting biological materials across a dark global map, symbolizing the supply chain challenges of emerging modalities
| 3 min read
A conceptual illustration of a scale balancing a sleek internal lab against a massive industrial factory, representing the strategic trade-off in outsourcing manufacturing for therapeutics.
| 3 min read
AI in biopharma manufacturing with digital twin and bioreactor illustrated by a split-screen composition. On the left side, a realistic, industrial stainless steel bioreactor in a sterile biopharma manufacturing facility, on the right side, a seamless transition into a glowing, translucent digital twin of the same bioreactor, constructed entirely of neon blue data streams
| 3 min read
A conceptual illustration showing a small glowing DNA helix expanding into massive industrial chemical reactors shaped like a double helix, representing the scaling of oligonucleotide synthesis from lab to factory.
| 3 min read
A high-tech molecular illustration depicting a PROTAC molecule bridging a target protein and an E3 ligase for ubiquitin tagging, with a proteasome "shredder" in the background, representing the targeted protein degradation mechanism.
| 3 min read
A conceptual illustration of a glowing DNA helix being edited like computer code via a futuristic digital interface, symbolizing the precise, programmable nature of RNA therapeutic clinical trial design.
| 4 min read
A conceptual illustration of a shattered glass DNA helix on a dark surface, with vibrant, glowing organic structures sprouting from the broken shards, symbolizing the lessons and progress gained from gene therapy failures.
| 4 min read
A conceptual medical illustration depicting glowing CAR-T cells navigating a complex biological maze inside a petri dish, symbolizing the regulatory and manufacturing hurdles of CAR-T approvals, set against a backdrop of clinical equipment and paperwork.
| 3 min read
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3D illustration of a single cell surrounded by small molecular particles in a red biological environment.
Measuring mRNA and protein together at single cell resolution can uncover tumor-specific signaling activity and immune features.
Illustration of an antibody intertwined with a DNA double helix.
Discover how CRISPR and single-cell RNA sequencing can connect disease-associated variants to regulatory elements, genes, and pathways.
Digital illustration of the human digestive system highlighting the liver, stomach, and intestines.
Explore how human gut-liver models can improve the translation of preclinical findings into clinical pharmacokinetic predictions.