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Ansa Biotechnologies raises $45 million to expand DNA synthesis

The funding round will support expanded US manufacturing and accelerate the company’s enzymatic DNA synthesis technology.
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EMERYVILLE, Calif. --(BUSINESS WIRE)-- Ansa Biotechnologies, Inc., a trusted partner for DNA synthesis, today announced that it has closed $45.2 million and secured commitments for an additional $9.2 million as part of an oversubscribed series B financing round. The round was led by Cerberus Ventures with participation from Blue Water Life Science Advisors, Altitude Life Science Ventures, and other existing investors. New investors include Fall Line Capital, AIM13, and Black Opal Ventures.

"We believe Ansa’s guaranteed approach fills a huge unmet need, and should become the new standard for DNA synthesis.”
- Chenny Zhang, Director at Cerberus Ventures.

As part of the financing, Chenny Zhang, Director at Cerberus Ventures, and Yanniv Dorone, Senior Vice President at Fall Line Capital, joined Ansa’s board of directors. They offer diverse industry experience and extensive technical expertise in key application fields, aiding Ansa’s long-term strategic goals.

The proceeds from this financing will enable Ansa to expand its US-based manufacturing capacity, enhance its focus on customer experience, and continue to advance strategic relationships and technological innovation. These efforts will allow Ansa to introduce novel applications, help customers accelerate their scientific progress at unprecedented speeds, and support the industry’s shift from reading genomes to writing them.

“Ansa is leading a fundamental shift in DNA synthesis,” said Zhang. “For decades, the market has been limited by an unreliable and outdated process. Ansa’s management team has done an excellent job demonstrating that scientists can finally get what they need, when they need it. We believe Ansa’s guaranteed approach fills a huge unmet need, and should become the new standard for DNA synthesis.”

Transforming DNA synthesis

Chemical DNA synthesis was foundational to the DNA reading era of biology, but it poses significant limitations as the industry transitions into the DNA writing era. The inability to reliably synthesize complex sequences or reach beyond modest lengths has stalled progress just as science is ready to move forward.

Ansa is redefining what is achievable with a proprietary enzymatic platform that provides both the length and complexity needed to design and assemble critical DNA constructs at scale. Unlike traditional chemical synthesis, Ansa’s sustainable enzymatic approach uses no harsh chemicals, preserving DNA integrity and enabling the synthesis of longer, more complex sequences. This capability unlocks previously inaccessible regions of the genome, empowering scientists to build new pathways, engineer innovative systems, and accelerate discoveries in gene and cell therapy, vaccines, agrigenomics, and synthetic biology.

Expanding what can be built

For decades, DNA synthesis has been limited to short, relatively simple constructs, leaving much of the genome out of reach. These constraints have kept scientists from designing at scale and building with the precision required to move biology into its next era.

Ansa is now delivering clonal DNA up to 50 kilobases in industry-leading times. By overcoming the twin barriers of length and complexity, Ansa provides researchers with the tools to design and assemble large DNA sequences that legacy providers cannot reliably produce.

Driving adoption and scaling for the future

Demand for Ansa’s services has surged rapidly in its first year of commercialization. The company recently introduced the Ansa On-Time Guarantee, a commitment to customers that their orders will be shipped in full and on time, or the entire order is free. Additionally, Ansa introduced a new pricing framework for low-complexity DNA sequences. This highly competitive pricing ensures access to high-quality DNA without compromising complexity or turnaround time.

“Our first year of commercialization proved what we already believed: reliability wins,” said Jason T. Gammack, CEO of Ansa Biotechnologies. “When you can deliver 50 kb of clonal DNA in 24 days or less, when you’re the only company bold enough to guarantee entire orders, and when you keep innovating on behalf of customers instead of protecting the status quo, you don’t just compete, you reset the rules. This financing is fuel for the next phase of our mission: to make DNA something scientists can count on, every single time.”

Entirely manufactured in the US, Ansa’s DNA products integrate seamlessly into existing workflows and are designed to empower the next wave of biological discovery. For more information about Ansa’s products, please visit www.ansabio.com/products.

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