Digital illustration of a human liver shape rendered in blue tones, composed of a geometric network of interconnected lines and nodes.
Application Note

AI-enabled 3D liver microtissue analysis for improved toxicity screening

Explore how combining 3D liver microtissue models with AI-driven image analysis enhances the accuracy and depth of hepatotoxicity assessment.

Drug-induced liver injury remains a major challenge in drug development. Three-dimensional liver microtissues better mimic native tissue biology but are difficult to analyze. To address this, advances in high-content imaging and machine learning now enable automated, multi-parametric analysis, revealing structural and phenotypic changes linked to compound-induced toxicity.

Download this application note to learn:

  • How AI-driven 3D segmentation improves quantitative analysis of microtissues
  • How multiplexed imaging captures multi-parametric cellular responses to compounds 
  • Strategies for phenotypic classification and data quality assessment in screening

Sponsored by

  • Molecular Devices

Top Image Credit:

Drypsiak