New oligonucleotide-based modalities, such as small interfering RNA and antisense oligonucleotides, are improving treatment options for many diseases. Since these therapeutics have human-specific targets, the need for physiologically relevant organ-on-a-chip models to assess drug delivery, efficacy, and safety continues to increase. In this webinar, Oliver Culley will explore how liver-on-a-chip technology enables researchers to delineate oligonucleotide distribution, uptake, and dosing to bridge the gap between preclinical studies and clinical success.
Topics to be covered
- The development challenges of oligonucleotide therapeutics
- Examining the impact of N-acetylgalactosamine-conjugated oligonucleotides on gene expression using liver-on-a-chip models
- Real-world case studies on liver-on-a-chip models in drug assessment
Tuesday, April 1st, 2025 | 10:00 AM - 11:00 AM Eastern Time
This webinar will be available to view live and on demand.
Speaker
Oliver Culley, PhD
Senior Scientist
CN Bio
