RNA editing catalyzed by adenosine deaminases acting on RNA (ADARs) occurs naturally at thousands of sites across the human transcriptome. This process profoundly affects gene expression and influences a wide range of human diseases from cancer to neurological disorders. In this webinar, Michael Breen will discuss the role of ADAR-mediated RNA editing in neurodevelopmental disorders and how his team develops site-directed RNA editing therapeutics.
Topics to be covered
- Studying RNA editing using transcriptome data and reporter assays
- Characterizing RNA editing across human brain regions, cell types, and brain development
Wednesday, April 5th, 2023 | 2:30 PM - 3:30 PM Eastern Time
This webinar will be available to view live and on demand.
Michael Breen, PhD
Icahn School of Medicine at Mount Sinai