| 2 min read
Register for free to listen to this article
Listen with Speechify
0:00
2:00
MedPharm, a leading clinical development organization in topical and transdermal drug delivery, recently announced that it has expanded its testing models to support pharmaceutical development programs targeting coronavirus treatments.
 
These models reportedly allow companies to assess therapeutic effectiveness in nasal, airway (bronchial), and deep lung (alveolar) epithelia against members of the Coronaviridae family. The use of such models is, in part, intended to help to de-risk development programs and screen drugs for therapeutic effectiveness to accelerate development prior to clinical trials.
 
“This new model allows companies to screen compounds and formulations to answer critical questions about effectiveness against viral infections in the Coronaviridae family prior to the clinic,” said Dr. Jon Lenn, MedPharm’s chief technology officer. “Finding effective new treatments quickly for these viral infections is imperative in these extraordinary times.”
 
MedPharm’s facility in North Carolina has a dedicated innovation laboratory, able to rapidly support the development of new types of in vitro pharmacodynamic/infection models. The dedicated microbiology lab has been specifically designed with negative internal pressure and biological safety cabinets suitable for BSL2 work. These models are based on air liquid interface tissue culture of primary human cells from different regions of the respiratory system which are then infected with relevant corona viral strains.   
 
MedPharm notes that it has a history of innovation in developing living tissue models to screen compounds and formulations.  This experience, company officials say, allows the company to quickly react and help solve project-specific problems for its customers and stay at the forefront of the latest scientific breakthroughs and technology.
 
Dr Jon Volmer, MedPharm’s Senior Director of Research Biology and Innovation, who has over 15 years experience in investigating of lung and respiratory disease at the University of North Carolina and the University of Texas, added: “We are looking forward to applying such a useful high throughput model to the development of new therapies for current and future coronaviruses”.  
 

Related Topics

Loading Next Article...
Loading Next Article...
Subscribe to Newsletter

Subscribe to our eNewsletters

Stay connected with all of the latest from Drug Discovery News.

Subscribe

Sponsored

Gold circles with attached purple corkscrew shapes represent gold nanoparticles against a black background.

Driving gene therapy with nonviral vectors 

Learn why nonviral vectors are on the rise in gene therapy development.
A 3D digital illustration of a viral spike protein on a cell surface, surrounded by colorful, floating antibodies in the background

Milestone: Leapfrogging to quantitative, high throughput protein detection and analysis

Researchers continuously push the boundaries of what’s possible with protein analysis tools.
Blue cancer cells attached to a cellular surface against a bright blue background in a 3D rendering of a cancer infection.

Advancing immuno-oncology research with cellular assays

Explore critical insights into immunogenicity and immunotoxicity assays for cancer therapies.
Drug Discovery News November 2024 Issue
Latest IssueVolume 20 • Issue 6 • November 2024

November 2024

November 2024 Issue

Explore this issue