Neuroscience
Repurposing an anesthetic for epilepsy
The general anesthesia drug propofol restores function to mutated signaling channels associated with epilepsy.
Immunology
Cancer Research
Dermatology
Internal Medicine
News
How transcription factor dynamics control immune responses
How transcription factor dynamics control immune responses
A changing dance of transcription factors modulates T regulatory cell gene expression in different immune contexts with implications for cancer and autoimmune diseases.
Hope for colon cancer in AbbVie’s antibody drug conjugate
Hope for colon cancer in AbbVie’s antibody drug conjugate
Manish Sharma led a clinical trial for a new antibody-drug conjugate that decreased tumor size in patients who had not responded to chemotherapy.
A spitting image of brain health
A spitting image of brain health
A saliva-based test could make it easier to diagnose concussions.
How monkeys revealed a schistosomiasis vaccine secret
How monkeys revealed a schistosomiasis vaccine secret
There is no vaccine against this parasitic worm infection, but rhesus macaques’ unique immune system has brought the prospect of a vaccine closer than ever.
Uncovering the mysterious antidepressant effects of ketamine
Uncovering the mysterious antidepressant effects of ketamine
Ketamine effectively treats depression, but recent studies illustrate the ongoing difficulties in understanding its antidepressant effects at a molecular level.
Watching an infection unfold with a sphingolipid probe
Watching an infection unfold with a sphingolipid probe
Scientists developed an unprecedented chemical tool to visualize sphingomyelin and sphingomyelinase activity during a chlamydia infection.
