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BD Biosciences: Basement membrane preparation
November 2008
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BD Matrigel Basement Membrane Matrix, from BD Biosciences, is certified LDEV-free. BD Matrigel is a solubilized basement membrane preparation extracted from the Engelbreth-Holm-Swarm mouse sarcoma, a tumor rich in extracellular matrix proteins. Major component is laminin, followed by collagen IV, heparan sulfate proteoglycans, entactin/nidogen. BD Matrigel is effective for the attachment and differentiation of both normal and transformed anchorage dependent epithelioid and other cell types. It is the basis for several types of tumor cell invasion assays, will support in vivo peripheral nerve regeneration, and provides the substrate necessary for the study of angiogenesis both in vitro and in vivo. For research use only. Not intended for use in diagnostic or therapeutic procedures.

 

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