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Promega and TOP srl create tools to enable live animal imaging for cancer studies
April 2010
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MADISON, Wisc.Promega and TOP srl recently announced they will partner on the development of tools for monitoring apoptosis in live mammals, an important biomarker in cancer studies. Under the agreement, the two companies are promoting the VivoGlo Caspase 3/7 Substrate for use with transgenic repTOP reporter mice. The tools allow the direct visualization and quantification of apoptosis non-invasively in live mice. The transgenic repTOP reporter mice will contain an improved luciferase luc2 gene from Promega, making it possible to study apoptotic processes in the whole live animal with these reporter mice with the same sensitivity and ease as in cell culture models.

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