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Horizon Discovery launches new companion diagnostics venture
February 2010
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CAMBRIDGE, England—Translational genomics firm Horizon Discovery announced in January that it has formed a new subsidiary venture, Horizon Dx Ltd. (HDx), to support the development, approval and sale of companion diagnostic products initially in the field of cancer. At the center of the venture will be Horizon's panel of more than 175 human isogenic cell models that recapitulate key drug sensitivity and resistance mechanisms in cancer patients. The first commercial products supplied by the new venture will be genetically defined mutant DNA and isogenic cell-admixtures situated within formalin fixed paraffin embedded samples. These control reagents will be used in conjunction with companion diagnostic kits that are currently enabling clinicians to ascertain which patients will respond to novel cancer therapies. Horizon is initially funding HDx from its balance sheet, but hopes to secure a multi-million dollar investment into the company by the end of the first half of 2010.
 

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